IL-21 ELISA Kit
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- Target See all IL-21 (IL21) ELISA Kits
- IL-21 (IL21) (Interleukin 21 (IL21))
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Reactivity
- Human
- Detection Method
- Colorimetric
- Method Type
- Sandwich ELISA
- Detection Range
- 31.25-2000 pg/mL
- Minimum Detection Limit
- 31.25 pg/mL
- Application
- ELISA
- Sample Type
- Cell Culture Supernatant, Serum, Plasma (heparin), Plasma (citrate), Plasma (EDTA)
- Analytical Method
- Quantitative
- Specificity
- Natural and recombinant Human IL-21 Ligand
- Sensitivity
- 15 pg/mL
- Material not included
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- Microplate reader.
- Pipettes and pipette tips.
- EP tube Deionized or distilled water.
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Interleukin 21 (IL21) ELISA Kit
IL21 Reactivity: Human Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Interleukin 21 (IL21) ELISA KitIL21 Reactivity: Mouse Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Interleukin 21 (IL21) ELISA KitIL21 Reactivity: Rat Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Interleukin 21 (IL21) ELISA KitSmall Sample IL21 Reactivity: Human Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Interleukin 21 (IL21) ELISA KitIL21 Reactivity: Mouse AA 25-146 Colorimetric Sandwich ELISA 62.5-4000 pg/mL Cell Culture Supernatant, Serum
Interleukin 21 (IL21) ELISA KitIL21 Reactivity: Cow Colorimetric Sandwich ELISA 0.41-100 ng/mL Cell Culture Supernatant, Plasma, Serum
Interleukin 21 (IL21) ELISA KitIL21 Reactivity: Mouse Colorimetric Sandwich ELISA 62.5-4000 pg/mL Cell Culture Supernatant, Serum
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- Application Notes
- Detection Wavelength: 450 nm
- Sample Volume
- 20 μL
- Assay Time
- 3 h
- Plate
- Pre-coated
- Restrictions
- For Research Use only
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- Storage
- 4 °C
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- Target See all IL-21 (IL21) ELISA Kits
- IL-21 (IL21) (Interleukin 21 (IL21))
- Alternative Name
- IL-21 (IL21 Products)
- Synonyms
- IL-21 ELISA Kit, Za11 ELISA Kit, interleukin 21 ELISA Kit, IL21 ELISA Kit, Il21 ELISA Kit
- Background
- Interleukin-21(IL-21) and its receptor play an important role in the regulation of the immune system. IL-21R, also called NILR (novel interleukin receptor), is a type I cytokine receptor with 4 conserved cysteine residues and an extracellular WSXWS motif. The biological effects of IL-21 include induction of differentiation of T-cells-stimulated B-cells into plasma cells and memory B-cells, stimulation (in conjuction) with IL-4 of IgG production, and induction of apoptotic effects in native B-cells and stimulated B-cells in the absence of T-cell signaling. Additionally, IL-21 promotes the anti-tumor activity of CD8+ T-cells and NK cells. IL-21 exerts its effect through binding to a specific type I cytokine receptor, IL-21R, which also contains the gamma chain found in other cytokine receptors including IL-2, IL-4, IL-7, IL-9 and IL-15. The IL-21/IL-21R interaction appears to play an important role in B and T cell proliferation after antigen stimulation and NK cell maturation.
- Pathways
- JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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