SERPINA12 ELISA Kit, 4632419J12Rik ELISA Kit, OL-64 ELISA Kit, Ol-64 ELISA Kit, Ol64 ELISA Kit, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 ELISA Kit, serpin family A member 12 ELISA Kit, serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 ELISA Kit, serpin A12 ELISA Kit, SERPINA12 ELISA Kit, Serpina12 ELISA Kit, LOC612386 ELISA Kit
Background
Vaspin (Visceral adipose tissue-derived serpin, Serpin A12), a serine protease inhibitor (serpin), is an insulin-sensitizing adipocytokine that has been isolated from both visceral and subcutaneous white adipose tissue. Based on recent findings, vaspin is suggested to regulate immune responses and inflammation and was found to be correlated with various metabolic parameters. Human vaspin blood levels are significantly increased in type 2 diabetes mellitus and obese patients. Thus vaspin may represent a novel biomarker for obesity and impaired insulin sensitivity and might serve as a new therapeutic target of metabolic syndrome.