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- Target
- Matrix Metalloproteinase
- Detection Method
- Fluorometric
- Application
- Fluorescence Resonance Energy Transfer Microscopy (FRET)
- Brand
- SensoLyte®
- Characteristics
- SensoLyte® 520 MMP Substrate Sampler Kit contains a series of FRET peptide substrates for use as fluorogenic indicators to assay MMP protease activities. It provides the best solution for identifying a suitable fluorogenic substrate for a particular MMP assay. All the MMP substrates in the kit are also available in bulk packages.
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- Comment
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FRET-based Assay Kit
- Restrictions
- For Research Use only
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- Handling Advice
- Keep Components A and B from light.
- Storage
- -20 °C
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Thymosin ? 4 gene silencing decreases stemness and invasiveness in glioblastoma." in: Brain : a journal of neurology, Vol. 137, Issue Pt 2, pp. 433-48, (2014) (PubMed).
: "Activated Abl kinase inhibits oncogenic transforming growth factor-beta signaling and tumorigenesis in mammary tumors." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 12, pp. 4231-43, (2009) (PubMed).
: "Systematic identification of substrates for profiling of secreted proteases from Aspergillus species." in: Journal of microbiological methods, Vol. 71, Issue 2, pp. 93-100, (2007) (PubMed).
: "Degradation of the Alzheimer disease amyloid beta-peptide by metal-dependent up-regulation of metalloprotease activity." in: The Journal of biological chemistry, Vol. 281, Issue 26, pp. 17670-80, (2006) (PubMed).
: "
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Thymosin ? 4 gene silencing decreases stemness and invasiveness in glioblastoma." in: Brain : a journal of neurology, Vol. 137, Issue Pt 2, pp. 433-48, (2014) (PubMed).
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- Target
- Matrix Metalloproteinase
- Alternative Name
- MMP
- Background
- Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated proteins capable of digesting extracellular matrix components. They are involved in diseases such as cancer, arthritis, asthma, angiogenesis, alopecia and metastasis. They are also identified as drug-screening targets.
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