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SensoLyte® Rh110 Cathepsin L Assay Kit

FRET Fluorometric
Catalog No. ABIN1882446
  • Target See all Cathepsin L (CTSL1) Kits
    Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))
    Detection Method
    Fluorometric
    Application
    Fluorescence Resonance Energy Transfer Microscopy (FRET)
    Brand
    SensoLyte®
    Characteristics
    The SensoLyte® Rh110 Cathepsin L Activity Assay Kit provides a convenient assay for screening Cathepsin L inhibitors or assay of enzyme activity using a fluorogenic substrate. Upon cleavage by Cathepsin L, this substrate generates the Rh110 (rhodamine 110) fluorophore with a bright green fluorescence that can be detected at excitation/emission=490/520 nm. The longer wavelength spectra and higher extinction coefficient of Rh110 provide greater sensitivity and less interference from other reaction components.
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    Discover our top product CTSL1 ELISA Kit
  • Comment

    FRET-based Assay Kit

    Restrictions
    For Research Use only
  • Handling Advice
    Protect Components A and B from light and moisture.
    Storage
    -80 °C
    Storage Comment
    Store all kit components at -20 °C, except Component C. Store Component C at -80 °C. Component D can be stored at room temperature for convenience.
  • Target
    Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))
    Alternative Name
    Cathepsin L (CTSL1 Products)
    Synonyms
    CATL Kit, CTSL1 Kit, MEP Kit, 1190035F06Rik Kit, Ctsl1 Kit, fs Kit, nkt Kit, CATHL Kit, CatL Kit, Ctsl Kit, CTSL Kit, mep Kit, catl Kit, ctsl Kit, cpl-1 Kit, MGC80629 Kit, MGC107932 Kit, LOC663234 Kit, 26-29-p Kit, Cp1 Kit, si:dkey-121a11.6 Kit, CTSV Kit, catL Kit, cb15 Kit, ctsl1b Kit, hgg1 Kit, wu:fb30g09 Kit, zgc:92089 Kit, cathepsin L Kit, cathepsin V Kit, cathepsin L L homeolog Kit, cathepsin L1 Kit, Cathepsin L1 Kit, Cathepsin L Kit, testin gene Kit, cathepsin 12 Kit, cathepsin Lb Kit, cathepsin L.1 Kit, CTSL Kit, Ctsl Kit, CTSV Kit, ctsl.L Kit, ctsl Kit, LOC100008830 Kit, catl1 Kit, 26-29-p Kit, catl Kit, Tsp_11596 Kit, Testin Kit, cts12 Kit, LOC102156614 Kit, ctslb Kit, ctsl.1 Kit
    Background
    Cathepsins are a class of globular lysosomal proteases, playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin L, a lysosomal endopeptidase, is a member of the papain-like family of cysteine proteinases. It is involved in the promotion of tumor cell invasion, antigen processing and turnover of intracellular and secreted proteins.
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