SensoLyte® Rh110 Cathepsin L Assay Kit
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- Target See all Cathepsin L (CTSL1) Kits
- Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))
- Detection Method
- Fluorometric
- Application
- Fluorescence Resonance Energy Transfer Microscopy (FRET)
- Brand
- SensoLyte®
- Characteristics
- The SensoLyte® Rh110 Cathepsin L Activity Assay Kit provides a convenient assay for screening Cathepsin L inhibitors or assay of enzyme activity using a fluorogenic substrate. Upon cleavage by Cathepsin L, this substrate generates the Rh110 (rhodamine 110) fluorophore with a bright green fluorescence that can be detected at excitation/emission=490/520 nm. The longer wavelength spectra and higher extinction coefficient of Rh110 provide greater sensitivity and less interference from other reaction components.
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- Discover our top product CTSL1 ELISA Kit
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- Comment
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FRET-based Assay Kit
- Restrictions
- For Research Use only
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- Handling Advice
- Protect Components A and B from light and moisture.
- Storage
- -80 °C
- Storage Comment
- Store all kit components at -20 °C, except Component C. Store Component C at -80 °C. Component D can be stored at room temperature for convenience.
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- Target
- Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))
- Alternative Name
- Cathepsin L (CTSL1 Products)
- Synonyms
- CATL Kit, CTSL1 Kit, MEP Kit, 1190035F06Rik Kit, Ctsl1 Kit, fs Kit, nkt Kit, CATHL Kit, CatL Kit, Ctsl Kit, CTSL Kit, mep Kit, catl Kit, ctsl Kit, cpl-1 Kit, MGC80629 Kit, MGC107932 Kit, LOC663234 Kit, 26-29-p Kit, Cp1 Kit, si:dkey-121a11.6 Kit, CTSV Kit, catL Kit, cb15 Kit, ctsl1b Kit, hgg1 Kit, wu:fb30g09 Kit, zgc:92089 Kit, cathepsin L Kit, cathepsin V Kit, cathepsin L L homeolog Kit, cathepsin L1 Kit, Cathepsin L1 Kit, Cathepsin L Kit, testin gene Kit, cathepsin 12 Kit, cathepsin Lb Kit, cathepsin L.1 Kit, CTSL Kit, Ctsl Kit, CTSV Kit, ctsl.L Kit, ctsl Kit, LOC100008830 Kit, catl1 Kit, 26-29-p Kit, catl Kit, Tsp_11596 Kit, Testin Kit, cts12 Kit, LOC102156614 Kit, ctslb Kit, ctsl.1 Kit
- Background
- Cathepsins are a class of globular lysosomal proteases, playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin L, a lysosomal endopeptidase, is a member of the papain-like family of cysteine proteinases. It is involved in the promotion of tumor cell invasion, antigen processing and turnover of intracellular and secreted proteins.
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