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- Target See all Cathepsin B (CTSB) Kits
- Cathepsin B (CTSB)
- Detection Method
- Fluorometric
- Application
- Fluorescence Resonance Energy Transfer Microscopy (FRET)
- Brand
- SensoLyte®
- Characteristics
- The SensoLyte® 440 Cathepsin B Assay Kit provides a fluorogenic peptide for measurement of enzyme activity. This peptide releases the AMC (7-amino-4-methylcoumarin) fluorophore upon cathepsin B cleavage and can be detected with excitation at 354 nm and emission at 442 nm.
- Top Product
- Discover our top product CTSB ELISA Kit
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- Comment
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FRET-based Assay Kit
- Restrictions
- For Research Use only
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- Handling Advice
- Protect Components A and B from light and moisture.
- Storage
- -80 °C
- Storage Comment
- Store all kit components at -20 °C, except for Component C. Store Component C at -80 °C. Component D can be stored at room temperature for convenience
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Galloyl moieties enhance the dentin biomodification potential of plant-derived catechins." in: Acta biomaterialia, Vol. 10, Issue 7, pp. 3288-94, (2014) (PubMed).
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Galloyl moieties enhance the dentin biomodification potential of plant-derived catechins." in: Acta biomaterialia, Vol. 10, Issue 7, pp. 3288-94, (2014) (PubMed).
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- Target
- Cathepsin B (CTSB)
- Alternative Name
- Cathepsin B (CTSB Products)
- Synonyms
- APPS Kit, CPSB Kit, CB Kit, apps Kit, cpsb Kit, LOC692390 Kit, CTSB Kit, cathepsin B Kit, cathepsin B S homeolog Kit, CTSB Kit, Ctsb Kit, ctsb.S Kit, LOC692390 Kit
- Background
- Cathepsins are a class of globular lysosomal proteases playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. The cathepsin family consists of 12 cysteine proteases with broad exo- and endopeptidase activity, of which Cathepsin B is a member. Elevated levels of cathepsin B were detected in metastases and neurological disorders including Alzheimer's disease (AD).
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