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KISS1 Products

(KiSS-1 Metastasis-Suppressor (KISS1))

Categories

This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH nuerons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues. [provided by RefSeq, Mar 2012].

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Featured KISS1 Categories

KISS1 Antibodies

High quality antibodies with extensive validation data.

KISS1 ELISA Kits

Reliable ELISA kits for a wide range of species.

KISS1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended KISS1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (4)
  • (4)
Cat. No. ABIN517344
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, ICC, IF
Validations
  • (4)
Cat. No. ABIN6266238
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (4)
Cat. No. ABIN6243764
Quantity 400 μL
Datasheet Datasheet

Recommended KISS1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6963314
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Competition ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6957322
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6973438
Quantity 96 tests
Datasheet Datasheet

Recommended KISS1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123691
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308711
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN934993
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our KISS1 products

Kudaibergenova, Aydogdu, Kandemir, Aydin: "Investigation of Kisspeptin Role in Experimental Kidney Ischemia/Reperfusion Injury." in: Folia medica, Vol. 62, Issue 1, pp. 82-88, (2021) (PubMed).

Calderón, Huerta, Galindo, González Casbas, Escobar-Morreale, Martín-Hidalgo, Botella-Carretero: "Lack of Improvement of Sperm Characteristics in Obese Males After Obesity Surgery Despite the Beneficial Changes Observed in Reproductive Hormones." in: Obesity surgery, Vol. 29, Issue 7, pp. 2045-2050, (2020) (PubMed).

Srivastava, Hiney, Dees: "Alcohol Delays the Onset of Puberty in the Female Rat by Altering Key Hypothalamic Events." in: Alcoholism, clinical and experimental research, Vol. 42, Issue 7, pp. 1166-1176, (2019) (PubMed).

Parlak, Türkkahraman, Ellidağ, Çelmeli, Parlak, Yılmaz: "Basal Serum Neurokinin B Levels in Differentiating Idiopathic Central Precocious Puberty from Premature Thelarche." in: Journal of clinical research in pediatric endocrinology, Vol. 9, Issue 2, pp. 101-105, (2018) (PubMed).

Yamasaki, Kuwahara, Iwasa, Yamamoto, Taniguchi, Yano, Matsui, Matsuzaki, Irahara: "Development-related changes in the expression of the ovarian Kiss1 and Kiss1r genes and their sensitivity to human chorionic gonadotropin in prepubertal female rats." in: The Journal of reproduction and development, Vol. 63, Issue 4, pp. 409-414, (2018) (PubMed).

Özgen, Torun, Bayraktar-Tanyeri, Durmaz, Kılıç, Cesur: "The relation of urinary bisphenol A with kisspeptin in girls diagnosed with central precocious puberty and premature thelarche." in: Journal of pediatric endocrinology & metabolism : JPEM, Vol. 29, Issue 3, pp. 337-41, (2016) (PubMed).

Çelik, Belviranli, Okudan: "Circulating levels of leptin, nesfatin-1 and kisspeptin in postmenopausal obese women." in: Archives of physiology and biochemistry, Vol. 122, Issue 4, pp. 195-199, (2016) (PubMed).

Srivastava, Hiney, Dees: "Manganese-Stimulated Kisspeptin Is Mediated by the IGF-1/Akt/Mammalian Target of Rapamycin Pathway in the Prepubertal Female Rat." in: Endocrinology, Vol. 157, Issue 8, pp. 3233-41, (2016) (PubMed).

Zhu, Li, Pan, Li, Zhang, Wang, Yang, Wu, Gong: "The Changes of Serum Leptin and Kisspeptin Levels in Chinese Children and Adolescents in Different Pubertal Stages." in: International journal of endocrinology, Vol. 2016, pp. 6790794, (2016) (PubMed).

Shin, Cho, Kang, Kim, Hong, Lee, Hong, Yoon: "KiSS-1 expression in oral squamous cell carcinoma and its prognostic significance." in: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, Vol. 124, Issue 4, pp. 291-8, (2016) (PubMed).

Synonyms and alternative names related to KISS1

KiSS-1 metastasis-suppressor (KISS1), KiSS-1 metastasis-suppressor (kiss1), KiSS-1 metastasis-suppressor (Kiss1), Eseptin, HH13, KiSS-1, metastatin

Protein level used designations for KISS1

  • kisspeptin-1
  • malignant melanoma metastasis-suppressor
  • metastasis-suppressor KiSS-1
  • metastin
  • prepro-kisspeptin
  • kisspeptin 1
  • 0610012C01Rik
  • Kiss1 metastasis-suppressor
  • Kiss1 variant E1a-E2b-E3
  • Kiss1 variant E1b-E2a-E3
  • Kiss1 variant E1b-E2b-E3
  • MLL septin-like fusion
  • kisspeptin
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