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KIR2DS4 Proteins

(Killer Cell Immunoglobulin-Like Receptor, Two Domains, Short Cytoplasmic Tail, 4 (KIR2DS4))

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008].

recommended

KIR2DS4 Protein (ABIN934899)

KIR2DS4 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % pure SDS

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recommended

KIR2DS4 Protein (AA 22-302) (His tag) (ABIN7403051)

KIR2DS4 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS, WB, Imm, PC

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KIR2DS4 Proteins by Origin

Find KIR2DS4 Proteins for a variety of species such as anti-Human KIR2DS4. The species listed below are among those available. Click on a link to go to the corresponding products.

KIR2DS4 Proteins by Source

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KIR2DS4 Proteins by Protein Type

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KIR2DS4 Proteins by Application

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Popular KIR2DS4 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

KIR2DS4 Protein

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN934899

Quantity 100 μg

Datasheet Datasheet

KIR2DS4 Protein (AA 22-302) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7403051

Quantity 100 μg

Datasheet Datasheet

Aliases for KIR2DS4 Proteins

killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4 (KIR2DS4) Proteins
CD158I Proteins
KIR1D Proteins
KIR412 Proteins
KKA3 Proteins
NKAT8 Proteins

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KIR2DS4 Proteins by Origin

KIR2DS4 Proteins by Source

KIR2DS4 Proteins by Protein Type

KIR2DS4 Proteins by Application

Popular KIR2DS4 Proteins

Aliases for KIR2DS4 Proteins

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