KIAA0586 Products
(KIAA0586)
Categories
Required for ciliogenesis and sonic hedgehog/SHH signaling (PubMed:21750036). Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes such as of PCM1. May play a role in early ciliogenesis in the disappearance of centriolar satellites that preceeds ciliary vesicle formation (By similarity). Involved in regulation of cell intracellular organization (PubMed:26386247). Involved in regulation of cell polarity (By similarity). Required for asymmetrical localization of CEP120 to daughter centrioles (PubMed:25251415). {ECO:0000250|UniProtKB:Q1G7G9, ECO:0000269|PubMed:21750036, ECO:0000269|PubMed:25251415, ECO:0000269|PubMed:26386247}.
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Recommended KIAA0586 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
ELISA, IHC
Validations
Cat. No.
ABIN7115666
Quantity
100 μg
Datasheet
Datasheet
Recommended KIAA0586 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6234290
Quantity
96 tests
Datasheet
Datasheet
Synonyms and alternative names related to KIAA0586
KIAA0586 (KIAA0586), Talpid3Protein level used designations for KIAA0586
- ortholog of chicken talpid{3}
- protein TALPID3
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