KEAP1 Products
(Kelch-Like ECH-Associated Protein 1 (KEAP1))
Categories
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured KEAP1 Categories
KEAP1 Antibodies
High quality antibodies with extensive validation data.
KEAP1 ELISA Kits
Reliable ELISA kits for a wide range of species.
KEAP1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended KEAP1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC, FACS
Validations
- (2)
- (5)
Cat. No.
ABIN1098141
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, ICC, FACS
Validations
- (2)
- (5)
Cat. No.
ABIN1098137
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC, IHC (p), FACS
Validations
- (8)
Cat. No.
ABIN1499016
Quantity
100 μL
Datasheet
Datasheet
Recommended KEAP1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6957270
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968103
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957269
Quantity
96 tests
Datasheet
Datasheet
Recommended KEAP1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1308530
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (21)
- (1)
Cat. No.
ABIN2724103
Quantity
20 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123669
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our KEAP1 products
: "Cannabidiol Regulates the Expression of Keratinocyte Proteins Involved in the Inflammation Process through Transcriptional Regulation." in: Cells, Vol. 8, Issue 8, (2020) (PubMed).: "Schisandrin C targets Keap1 and attenuates oxidative stress by activating Nrf2 pathway in Ang II-challenged vascular endothelium." in: Phytotherapy research : PTR, Vol. 33, Issue 3, pp. 779-790, (2019) (PubMed).
: "Brusatol Enhances the Chemotherapy Efficacy of Gemcitabine in Pancreatic Cancer via the Nrf2 Signalling Pathway." in: Oxidative medicine and cellular longevity, Vol. 2018, pp. 2360427, (2018) (PubMed).
: "Targeting the proinflammatory cytokines, oxidative stress, apoptosis and TGF-β1/STAT-3 signaling by irbesartan to ameliorate doxorubicin-induced hepatotoxicity." in: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, Vol. 24, Issue 8, pp. 623-631, (2018) (PubMed).
: "Ameliorative potential of linagliptin and/or calcipotriol on bleomycin-induced lung fibrosis: In vivo and in vitro study." in: Environmental toxicology and pharmacology, Vol. 50, pp. 216-226, (2017) (PubMed).
: "The electrophilic character of quinones is essential for the suppression of Bach1." in: Toxicology, Vol. 387, pp. 17-26, (2017) (PubMed).
: "Selenium antagonizes cadmium-induced apoptosis in chicken spleen but not involving Nrf2-regulated antioxidant response." in: Ecotoxicology and environmental safety, Vol. 145, pp. 503-510, (2017) (PubMed).
: "Induction of Mkp-1 and Nuclear Translocation of Nrf2 by Limonoids from Khaya grandifoliola C.DC Protect L-02 Hepatocytes against Acetaminophen-Induced Hepatotoxicity." in: Frontiers in pharmacology, Vol. 8, pp. 653, (2017) (PubMed).
: "Caveolin-1 Expression Ameliorates Nephrotic Damage in a Rabbit Model of Cholesterol-Induced Hypercholesterolemia." in: PLoS ONE, Vol. 11, Issue 4, pp. e0154210, (2016) (PubMed).
: "Rotavirus NSP1 Associates with Components of the Cullin RING Ligase Family of E3 Ubiquitin Ligases." in: Journal of virology, Vol. 90, Issue 13, pp. 6036-48, (2016) (PubMed).
Synonyms and alternative names related to KEAP1
kelch like ECH associated protein 1 (KEAP1), kelch-like ECH-associated protein 1 (Keap1), Kelch-like ECH-associated protein 1 (Keap1), kelch-like ECH-associated protein 1a (keap1a), kelch like ECH associated protein 1 (keap1), kelch like ECH associated protein 1 L homeolog (keap1.L), kelch like ECH associated protein 1 (Keap1), kelch-like ECH-associated protein 1b (keap1b), fb36f11, INrf2, INRF2, Inrf2, keap1, KEAP1, KLHL19, klhl19, mKIAA0132, wu:fb36f11, zgc:171654Protein level used designations for KEAP1
- cytosolic inhibitor of Nrf2
- kelch-like family member 19
- kelch-like protein 19
- NRF2 cytosolic inhibitor
- ring canal protein
- kelch-like ECH-associated protein 1
- klhl19
- LOW QUALITY PROTEIN: kelch-like ECH-associated protein 1
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