Kdm6b Products
(Lysine (K)-Specific Demethylase 6B (Kdm6b))
Categories
Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.
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Featured Kdm6b Categories
Kdm6b Antibodies
High quality antibodies with extensive validation data.
Kdm6b ELISA Kits
Reliable ELISA kits for a wide range of species.
Recommended Kdm6b Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p)
Validations
- (15)
- (3)
Cat. No.
ABIN387862
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IF
Validations
- (4)
Cat. No.
ABIN6142806
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC
Validations
- (5)
Cat. No.
ABIN3031660
Quantity
0.2 mL
Datasheet
Datasheet
Recommended Kdm6b ELISA Kits
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Reactivity
Analytical Method
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Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957577
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Sandwich ELISA
Validations
Cat. No.
ABIN422442
Quantity
96 tests
Datasheet
Datasheet
Latest Publications for our Kdm6b products
: "Endogenous hydrogen sulfide regulates histone demethylase JMJD3-mediated inflammatory response in LPS-stimulated macrophages and in a mouse model of LPS-induced septic shock." in: Biochemical pharmacology, Vol. 149, pp. 153-162, (2018) (PubMed).: "Critical role of histone demethylase Jumonji domain-containing protein 3 in the regulation of neointima formation following vascular injury." in: Cardiovascular research, Vol. 114, Issue 14, pp. 1894-1906, (2018) (PubMed).
: "Ehrlichia chaffeensis Tandem Repeat Effector Targets Differentially Influence Infection." in: Frontiers in cellular and infection microbiology, Vol. 7, pp. 178, (2017) (PubMed).
: "Cyclical DNA Methylation and Histone Changes Are Induced by LPS to Activate COX-2 in Human Intestinal Epithelial Cells." in: PLoS ONE, Vol. 11, Issue 6, pp. e0156671, (2017) (PubMed).
: "Structure of Nascent Chromatin Is Essential for Hematopoietic Lineage Specification." in: Cell reports, Vol. 19, Issue 2, pp. 295-306, (2017) (PubMed).
: "Generation of an anti-EpCAM antibody and epigenetic regulation of EpCAM in colorectal cancer." in: International journal of oncology, Vol. 46, Issue 4, pp. 1788-800, (2015) (PubMed).
: "Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma." in: Nature medicine, (2014) (PubMed).
: "Molecular mechanism of Jmjd3-mediated interleukin-6 gene regulation in endothelial cells underlying spinal cord injury." in: Journal of neurochemistry, Vol. 122, Issue 2, pp. 272-82, (2013) (PubMed).
: "Opposing roles of STAT4 and Dnmt3a in Th1 gene regulation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 2, pp. 902-11, (2013) (PubMed).
: "Histone demethylase KDM6B promotes epithelial-mesenchymal transition." in: The Journal of biological chemistry, Vol. 287, Issue 53, pp. 44508-17, (2012) (PubMed).
Synonyms and alternative names related to Kdm6b
lysine (K)-specific demethylase 6B (kdm6b), lysine demethylase 6B (KDM6B), lysine (K)-specific demethylase 6B, b (kdm6bb), KDM1 lysine (K)-specific demethylase 6B (Kdm6b), lysine demethylase 6B (Kdm6b), 1700064E03Rik, BC038313, jmjd3, Jmjd3, JMJD3, kdm6b, mKIAA0346, si:ch211-237l4.7Protein level used designations for Kdm6b
- jumonji domain containing 3
- lysine (K)-specific demethylase 6B
- jumonji domain containing 3, histone lysine demethylase
- lysine-specific demethylase 6B-like
- jmjC domain-containing protein 3
- jumonji domain-containing protein 3
- lysine-specific demethylase 6B
- lysine demethylase 6B
- jumonji domain-containing 3
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