KDM5B Products
(Lysine (K)-Specific Demethylase 5B (KDM5B))
Categories
Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor (By similarity).
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Featured KDM5B Categories
KDM5B Antibodies
High quality antibodies with extensive validation data.
KDM5B Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended KDM5B Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (3)
- (8)
Cat. No.
ABIN1327126
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, FACS
Validations
- (4)
Cat. No.
ABIN5542656
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (3)
Cat. No.
ABIN762986
Quantity
100 μL
Datasheet
Datasheet
Recommended KDM5B Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Insect cells (Sf9)
Validations
- (3)
Cat. No.
ABIN2669681
Quantity
20 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308520
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Baculovirus infected Insect Cells, Insect cells (Sf9), Mouse
Validations
Cat. No.
ABIN6700242
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our KDM5B products
: "Sequence-dependent cross-resistance of combined radiotherapy plus BRAFV600E inhibition in melanoma. ..." in: European journal of cancer (Oxford, England : 1990), Vol. 109, pp. 137-153, (2019) (PubMed).: "Targeting the H3K4 demethylase KDM5B reprograms the metabolome and phenotype of melanoma cells." in: The Journal of investigative dermatology, (2019) (PubMed).
: "Blockade of Immune-Checkpoint B7-H4 and Lysine Demethylase 5B in Esophageal Squamous Cell Carcinoma Confers Protective Immunity against P. gingivalis Infection." in: Cancer immunology research, Vol. 7, Issue 9, pp. 1440-1456, (2019) (PubMed).
: "CD271 Expression on Patient Melanoma Cells Is Unstable and Unlinked to Tumorigenicity." in: Cancer research, Vol. 76, Issue 13, pp. 3965-77, (2016) (PubMed).
: "Aberrant KDM5B expression promotes aggressive breast cancer through MALAT1 overexpression and downregulation of hsa-miR-448." in: BMC cancer, Vol. 16, pp. 160, (2016) (PubMed).
: "PLU-1/JARID1B overexpression predicts proliferation properties in head and neck squamous cell carcinoma." in: Oncology reports, Vol. 33, Issue 5, pp. 2454-60, (2015) (PubMed).
: "SKP2 inactivation suppresses prostate tumorigenesis by mediating JARID1B ubiquitination." in: Oncotarget, Vol. 6, Issue 2, pp. 771-88, (2015) (PubMed).
: "Overexpression of JARID1B is associated with poor prognosis and chemotherapy resistance in epithelial ovarian cancer." in: Tumour biology, Vol. 36, Issue 4, pp. 2465-72, (2015) (PubMed).
: "The histone-H3K4-specific demethylase KDM5B binds to its substrate and product through distinct PHD fingers." in: Cell reports, Vol. 6, Issue 2, pp. 325-35, (2014) (PubMed).
: "Inverse regulation of melanoma growth and migration by Orai1/STIM2-dependent calcium entry." in: Pigment cell & melanoma research, Vol. 27, Issue 3, pp. 442-53, (2014) (PubMed).
Synonyms and alternative names related to KDM5B
lysine (K)-specific demethylase 5Ba (kdm5ba), lysine (K)-specific demethylase 5Bb (kdm5bb), lysine demethylase 5B (KDM5B), lysine (K)-specific demethylase 5B (Kdm5b), lysine (K)-specific demethylase 5B (KDM5B), lysine demethylase 5B (Kdm5b), 2010009J12Rik, 2210016I17Rik, AW556288, cb264, CT31, D1Ertd202e, id:ibd5050, jarid1b, JARID1B, Jarid1b, jarid1ba, jarid1bb, mKIAA4034, PLU-1, plu1, PLU1, Plu1, PUT1, Rb-Bp2, RBBP2H1A, RGD1565602, wu:fc44h11, wu:fd15c05, zgc:85741Protein level used designations for KDM5B
- jumonji, AT rich interactive domain 1B (Rbp2 like)
- jumonji, AT rich interactive domain 1Ba (Rbp2 like)
- histone demethylase JARID1B-B
- jumonji/ARID domain-containing protein 1B-B
- lysine-specific demethylase 5B-B
- putative DNA/chromatin binding motif
- lysine (K)-specific demethylase 5B
- Jumonji, AT rich interactive domain 1B (RBP2-like)
- jumonji, AT rich interactive domain 1B
- lysine-specific demethylase 5B-like
- RBP2-H1
- cancer/testis antigen 31
- histone demethylase JARID1B
- jumonji/ARID domain-containing protein 1B
- lysine-specific demethylase 5B
- retinoblastoma-binding protein 2 homolog 1
- retinoblastoma-binding protein 2, homolog 1A
- putative DNA/chromatin binding motif 1
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