KDM4B Products
(Lysine (K)-Specific Demethylase 4B (KDM4B))
Categories
Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.
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Featured KDM4B Categories
KDM4B Antibodies
High quality antibodies with extensive validation data.
KDM4B Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended KDM4B Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, FACS
Validations
- (4)
Cat. No.
ABIN5611347
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IP
Validations
- (4)
Cat. No.
ABIN7268329
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (3)
Cat. No.
ABIN653341
Quantity
400 μL
Datasheet
Datasheet
Recommended KDM4B Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3093321
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3136790
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Baculovirus infected Insect Cells, Insect cells (Sf9), Mouse
Validations
Cat. No.
ABIN6700238
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our KDM4B products
: "SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy." in: PLoS pathogens, Vol. 14, Issue 5, pp. e1007071, (2018) (PubMed).: "Histone H3K9 demethylase JMJD2B induces hepatic steatosis through upregulation of PPARγ2." in: Scientific reports, Vol. 8, Issue 1, pp. 13734, (2018) (PubMed).
: "Histone demethylase KDM4B regulates otic vesicle invagination via epigenetic control of Dlx3 expression." in: The Journal of cell biology, Vol. 211, Issue 4, pp. 815-27, (2015) (PubMed).
: "RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites." in: The EMBO journal, Vol. 31, Issue 8, pp. 1865-78, (2012) (PubMed).
: "The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6." in: Cancer prevention research (Philadelphia, Pa.), Vol. 4, Issue 12, pp. 2051-61, (2011) (PubMed).
: "The histone demethylases JMJD1A and JMJD2B are transcriptional targets of hypoxia-inducible factor HIF." in: The Journal of biological chemistry, Vol. 283, Issue 52, pp. 36542-52, (2008) (PubMed).
Synonyms and alternative names related to KDM4B
lysine demethylase 4B (KDM4B), lysine (K)-specific demethylase 4B (kdm4b), lysine (K)-specific demethylase 4B (KDM4B), lysine demethylase 4B (kdm4b), lysine (K)-specific demethylase 4B (Kdm4b), 4732474L06Rik, JMJD2B, jmjd2b, Jmjd2b, KDM4B, mKIAA0876, si:ch211-124a3.4, TDRD14BProtein level used designations for KDM4B
- lysine (K)-specific demethylase 4B
- jumonji domain containing 2B
- lysine-specific demethylase 4B
- lysine-specific demethylase 4B-like
- jmjC domain-containing histone demethylation protein 3B
- jumonji domain-containing protein 2B
- tudor domain containing 14B
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