KDM4A Products
(Lysine (K)-Specific Demethylase 4A (KDM4A))
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This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor. [provided by RefSeq, Apr 2009].
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Featured KDM4A Categories
KDM4A Antibodies
High quality antibodies with extensive validation data.
KDM4A ELISA Kits
Reliable ELISA kits for a wide range of species.
KDM4A Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended KDM4A Antibodies
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Reactivity
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Validations
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Human
Application
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- (6)
Cat. No.
ABIN7441397
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, ICC, FACS
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Cat. No.
ABIN5542632
Quantity
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Datasheet
Reactivity
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Application
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Cat. No.
ABIN969230
Quantity
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Recommended KDM4A ELISA Kits
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Analytical Method
Quantitative Sandwich ELISA
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Cat. No.
ABIN6957575
Quantity
96 tests
Datasheet
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Reactivity
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Analytical Method
Quantitative Sandwich ELISA
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Cat. No.
ABIN5656536
Quantity
96 tests
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Recommended KDM4A Proteins
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Source
Escherichia coli (E. coli)
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- (1)
Cat. No.
ABIN7123808
Quantity
50 μg
Datasheet
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Reactivity
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Source
Baculovirus
Validations
- (2)
Cat. No.
ABIN2669705
Quantity
20 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7408756
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our KDM4A products
: "SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy." in: PLoS pathogens, Vol. 14, Issue 5, pp. e1007071, (2018) (PubMed).: "The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway." in: Nature communications, Vol. 7, pp. 12700, (2016) (PubMed).
: "Lamin A/C-dependent interaction with 53BP1 promotes cellular responses to DNA damage." in: Aging cell, Vol. 14, Issue 2, pp. 162-9, (2015) (PubMed).
: "KDM4B and KDM4A promote endometrial cancer progression by regulating androgen receptor, c-myc, and p27kip1." in: Oncotarget, Vol. 6, Issue 31, pp. 31702-20, (2015) (PubMed).
: "Community resources and technologies developed through the NIH Roadmap Epigenomics Program." in: Methods in molecular biology (Clifton, N.J.), Vol. 1238, pp. 27-49, (2014) (PubMed).
: "JMJD2A attenuation affects cell cycle and tumourigenic inflammatory gene regulation in lipopolysaccharide stimulated neuroectodermal stem cells." in: Experimental cell research, Vol. 328, Issue 2, pp. 361-78, (2014) (PubMed).
: "FBXO22 protein is required for optimal synthesis of the N-methyl-D-aspartate (NMDA) receptor coagonist D-serine." in: The Journal of biological chemistry, Vol. 289, Issue 49, pp. 33904-15, (2014) (PubMed).
: "Comparison of differentiation potential of male mouse adipose tissue and bone marrow derived-mesenchymal stem cells into germ cells." in: Iranian journal of reproductive medicine, Vol. 11, Issue 12, pp. 965-76, (2014) (PubMed).
: "Kdm4b histone demethylase is a DNA damage response protein and confers a survival advantage following γ-irradiation." in: The Journal of biological chemistry, Vol. 288, Issue 29, pp. 21376-88, (2013) (PubMed).
: "The JMJD2A demethylase regulates apoptosis and proliferation in colon cancer cells." in: Journal of cellular biochemistry, Vol. 113, Issue 4, pp. 1368-76, (2012) (PubMed).
Synonyms and alternative names related to KDM4A
lysine demethylase 4A (KDM4A), lysine-specific demethylase 4A (LOC100228023), lysine (K)-specific demethylase 4A (KDM4A), lysine (K)-specific demethylase 4A (Kdm4a), lysine demethylase 4A (Kdm4a), D4Ertd222e, JHDM3A, JMJD2, Jmjd2, JMJD2A, Jmjd2a, mKIAA0677, TDRD14AProtein level used designations for KDM4A
- jumonji domain containing 2A
- lysine (K)-specific demethylase 4A
- lysine-specific demethylase 4A
- jumonji domain-containing protein 2A
- JmjC domain-containing histone demethylation protein 3A
- jumonji domain-containing 2A
- lysine-specific demethylase 4A-like
- jmjC domain-containing histone demethylation protein 3A
- jumonji C domain-containing histone demethylase 3A
- jumonji domain containing 2
- tudor domain containing 14A
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