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KDELR3 Products

(KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 3 (kDELR3))

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Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR3 was the third member of the family to be identified, and it encodes a protein highly homologous to KDELR1 and KDELR2 proteins. Two transcript variants of KDELR3 that arise by alternative splicing, and encode different isoforms of KDELR3 receptor, have been described. [provided by RefSeq, Jul 2008].

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Featured KDELR3 Categories

KDELR3 Antibodies

High quality antibodies with extensive validation data.

KDELR3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended KDELR3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, ELISA, ICC, IF
Validations
  • (2)
Cat. No. ABIN6261593
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7187130
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (1)
Cat. No. ABIN3185290
Quantity 100 μL
Datasheet Datasheet

Recommended KDELR3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308518
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3110166
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3126633
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our KDELR3 products

Collins, Wright, Edwards, Davis, Grinham, Cole, Goward, Aguado, Mallya, Mokrab, Huckle, Beare, Dunham: "A genome annotation-driven approach to cloning the human ORFeome." in: Genome biology, Vol. 5, Issue 10, pp. R84, (2004) (PubMed).

Synonyms and alternative names related to KDELR3

KDEL endoplasmic reticulum protein retention receptor 3 (KDELR3), KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 (Kdelr3), KDEL endoplasmic reticulum protein retention receptor 3 L homeolog (kdelr3.L), KDEL endoplasmic reticulum protein retention receptor 3 (Kdelr3), AI173274, ERD2, ERD2L3, kdelr

Protein level used designations for KDELR3

  • ER lumen protein retaining receptor 3
  • KDEL endoplasmic reticulum protein retention receptor 3
  • KDEL receptor 3
  • endoplasmic reticulum lumen protein retaining receptor
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