KDELR2 Products
(KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 2 (KDELR2))
Categories
Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR2 was the second member of the family to be identified, and it encodes a protein which is 83% identical to the KDELR1 gene product. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008].
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Featured KDELR2 Categories
KDELR2 Antibodies
High quality antibodies with extensive validation data.
KDELR2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended KDELR2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, IF
Validations
- (1)
Cat. No.
ABIN7187129
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (1)
Cat. No.
ABIN6258945
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF
Validations
- (1)
Cat. No.
ABIN3185289
Quantity
100 μL
Datasheet
Datasheet
Recommended KDELR2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308516
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3097430
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3128337
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our KDELR2 products
: "Mesencephalic astrocyte-derived neurotrophic factor (MANF) secretion and cell surface binding are modulated by KDEL receptors." in: The Journal of biological chemistry, Vol. 288, Issue 6, pp. 4209-25, (2013) (PubMed).Synonyms and alternative names related to KDELR2
KDEL endoplasmic reticulum protein retention receptor 2 L homeolog (kdelr2.L), KDEL endoplasmic reticulum protein retention receptor 2 (KDELR2), KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 (Kdelr2), KDEL endoplasmic reticulum protein retention receptor 2 (Kdelr2), KDEL endoplasmic reticulum protein retention receptor 1 L homeolog (kdelr1.L), 1110007A14Rik, ELP-1, ERD2.2, kdelr1-a, kdelr2Protein level used designations for KDELR2
- ER lumen protein retaining receptor 2
- KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
- KDEL endoplasmic reticulum protein retention receptor 2
- KDEL receptor 2
- (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
- ERD-2-like protein
- ERD2-like protein 1
- ER lumen protein retaining receptor 1-A
- KDEL endoplasmic reticulum protein retention receptor 1-A
- KDEL receptor 1-A
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