KDELR1 Products
(KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 1 (KDELR1))
Categories
Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, which is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. The protein encoded by this gene was the first member of the family to be identified, and it encodes a protein structurally and functionally similar to the yeast ERD2 gene product. [provided by RefSeq, Jul 2008].
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Featured KDELR1 Categories
KDELR1 Antibodies
High quality antibodies with extensive validation data.
KDELR1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended KDELR1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, IHC, ICC
Validations
- (3)
Cat. No.
ABIN6262763
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Human, Monkey, Mouse, Rat
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN1742422
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, FACS, IF (cc), IF (p), IHC (p)
Validations
Cat. No.
ABIN6943880
Quantity
100 μL
Datasheet
Datasheet
Recommended KDELR1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308514
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3097037
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3127873
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our KDELR1 products
: "Mesencephalic astrocyte-derived neurotrophic factor (MANF) secretion and cell surface binding are modulated by KDEL receptors." in: The Journal of biological chemistry, Vol. 288, Issue 6, pp. 4209-25, (2013) (PubMed).Synonyms and alternative names related to KDELR1
KDEL endoplasmic reticulum protein retention receptor 1 (KDELR1), KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 (Kdelr1), KDEL endoplasmic reticulum protein retention receptor 1 (Kdelr1), 8030486F04Rik, AW215843, ERD2, ERD2.1, Erd2.1, HDEL, PM23Protein level used designations for KDELR1
- ER lumen protein retaining receptor 1
- KDEL endoplasmic reticulum protein retention receptor 1
- KDEL receptor 1
- putative MAPK-activating protein PM23
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