KCNU1 Products
(Potassium Channel, Subfamily U, Member 1 (KCNU1))
Categories
Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K(+). May be involved in sperm capacitation and/or the acrosome reaction, essential steps in fertilization where changes in both intracellular pH and membrane potential are known to occur. In contrast to KCNMA1/SLO1, it is not activated by Ca(2+) or Mg(2+) (By similarity).
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Featured KCNU1 Categories
KCNU1 Antibodies
High quality antibodies with extensive validation data.
KCNU1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended KCNU1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC, ELISA
Validations
- (1)
Cat. No.
ABIN7245455
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN7269471
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6293996
Quantity
20 μL
Datasheet
Datasheet
Recommended KCNU1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3109066
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3131830
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our KCNU1 products
: "SLO3 auxiliary subunit LRRC52 controls gating of sperm KSPER currents and is critical for normal fertility." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 8, pp. 2599-604, (2015) (PubMed).: "Deletion of the Slo3 gene abolishes alkalization-activated K+ current in mouse spermatozoa." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 14, pp. 5879-84, (2011) (PubMed).
: "LRRC52 (leucine-rich-repeat-containing protein 52), a testis-specific auxiliary subunit of the alkalization-activated Slo3 channel." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 48, pp. 19419-24, (2011) (PubMed).
: "The SLO3 sperm-specific potassium channel plays a vital role in male fertility." in: FEBS letters, Vol. 584, Issue 5, pp. 1041-6, (2010) (PubMed).
: "Mouse sperm K+ currents stimulated by pH and cAMP possibly coded by Slo3 channels." in: Biochemical and biophysical research communications, Vol. 381, Issue 2, pp. 204-9, (2009) (PubMed).
: "A novel, single, transmembrane protein CATSPERG is associated with CATSPER1 channel protein." in: Biology of reproduction, Vol. 81, Issue 3, pp. 539-44, (2009) (PubMed).
: "Interactions between beta subunits of the KCNMB family and Slo3: beta4 selectively modulates Slo3 expression and function." in: PLoS ONE, Vol. 4, Issue 7, pp. e6135, (2009) (PubMed).
Synonyms and alternative names related to KCNU1
potassium channel, subfamily U, member 1 (Kcnu1), potassium calcium-activated channel subfamily U member 1 (KCNU1), KCa5, KCa5.1, Kcnma3, KCNMC1, mSlo3, Slo3Protein level used designations for KCNU1
- KSper
- calcium-activated potassium channel subunit alpha-3
- calcium-activated potassium channel, subfamily M subunit alpha-3
- pH-sensitive maxi potassium channel
- pore-forming subunit of the sperm-specific alkalization activated K(+) current
- potassium channel subfamily U member 1
- potassium large conductance pH-sensitive channel, subfamily M, alpha member 3
- slowpoke homolog 3
- Calcium-activated potassium channel subunit alpha-3
- Calcium-activated potassium channel, subfamily M subunit alpha-3
- Slowpoke homolog 3
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