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KCNN2 Products

(Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 2 (KCNN2))
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured KCNN2 Categories

KCNN2 Antibodies

High quality antibodies with extensive validation data.

KCNN2 ELISA Kits

Reliable ELISA kits for a wide range of species.

KCNN2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended KCNN2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC, ELISA, ICC, FACS
Validations
  • (5)
Cat. No. ABIN5542523
Quantity 100 μL
Datasheet Datasheet

Application WB, IHC
Validations
  • (1)
  • (5)
Cat. No. ABIN2776144
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7189257
Quantity 100 μg
Datasheet Datasheet

Recommended KCNN2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958694
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1570877
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5657987
Quantity 96 tests
Datasheet Datasheet

Recommended KCNN2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7386002
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3118075
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3134537
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our KCNN2 products

Chakroborty, Kim, Schneider, Jacobson, Molgó, Stutzmann: "Early presynaptic and postsynaptic calcium signaling abnormalities mask underlying synaptic depression in presymptomatic Alzheimer's disease mice." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 24, pp. 8341-53, (2012) (PubMed).

Morimoto, Ohya, Hayashi, Onozaki, Imaizumi: "Cell-cycle-dependent regulation of Ca2+-activated K+ channel in Jurkat T-lymphocyte." in: Journal of pharmacological sciences, Vol. 104, Issue 1, pp. 94-8, (2007) (PubMed).

Synonyms and alternative names related to KCNN2

potassium calcium-activated channel subfamily N member 2 (KCNN2), potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 (Kcnn2), potassium calcium-activated channel subfamily N member 2 (Kcnn2), fri, hSK2, KCa2.2, KCNN2, SK2, SKCA2, SKCa 2

Protein level used designations for KCNN2

  • potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
  • small conductance calcium-activated potassium channel protein 2
  • small-conductance calcium-activated potassium channel
  • apamin-sensitive small-conductance Ca2+-activated potassium channel
  • small conductance potassium channel type 2
  • SKCa 2
  • small conductance calcium-activated potassium channel subfamily N member 2
  • SK2
  • SKCa2
  • small conductance calcium-activated channel, subfamily N, member 2
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