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KCNMB2 Products

(Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 2 (KCNMB2))

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MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents. Two variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured KCNMB2 Categories

KCNMB2 Antibodies

High quality antibodies with extensive validation data.

KCNMB2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended KCNMB2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (2)
Cat. No. ABIN6257763
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB
Validations
  • (2)
Cat. No. ABIN6242864
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (5)
  • (1)
Cat. No. ABIN1881476
Quantity 400 μL
Datasheet Datasheet

Recommended KCNMB2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308466
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3119545
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3128726
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our KCNMB2 products

Martinez-Espinosa, Yang, Gonzalez-Perez, Xia, Lingle: "Knockout of the BK ?2 subunit abolishes inactivation of BK currents in mouse adrenal chromaffin cells and results in slow-wave burst activity." in: The Journal of general physiology, Vol. 144, Issue 4, pp. 275-95, (2014) (PubMed).

Zhang, Mok, Lee, Charbonnet, Gold: "Inflammation-induced changes in BK(Ca) currents in cutaneous dorsal root ganglion neurons from the adult rat." in: Molecular pain, Vol. 8, pp. 37, (2012) (PubMed).

Treviño, Yang, French, Hunger, Carroll, Devidas, Willman, Neale, Downing, Raimondi, Pui, Evans, Relling: "Germline genomic variants associated with childhood acute lymphoblastic leukemia." in: Nature genetics, Vol. 41, Issue 9, pp. 1001-5, (2009) (PubMed).

Lee, Cui: "{beta} subunit-specific modulations of BK channel function by a mutation associated with epilepsy and dyskinesia." in: The Journal of physiology, Vol. 587, Issue Pt 7, pp. 1481-98, (2009) (PubMed).

Zarei, Song, Wilson, Cox, Colom, Knaus, Stefani, Toro: "Endocytic trafficking signals in KCNMB2 regulate surface expression of a large conductance voltage and Ca(2+)-activated K+ channel." in: Neuroscience, Vol. 147, Issue 1, pp. 80-9, (2007) (PubMed).

Zeng, Benzinger, Xia, Lingle: "BK channels with beta3a subunits generate use-dependent slow afterhyperpolarizing currents by an inactivation-coupled mechanism." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 17, pp. 4707-15, (2007) (PubMed).

Orio, Torres, Rojas, Carvacho, Garcia, Toro, Valverde, Latorre: "Structural determinants for functional coupling between the beta and alpha subunits in the Ca2+-activated K+ (BK) channel." in: The Journal of general physiology, Vol. 127, Issue 2, pp. 191-204, (2006) (PubMed).

Synonyms and alternative names related to KCNMB2

potassium calcium-activated channel subfamily M regulatory beta subunit 2 (KCNMB2), potassium large conductance calcium-activated channel, subfamily M, beta member 2 (kcnmb2), potassium large conductance calcium-activated channel, subfamily M, beta member 2 (Kcnmb2), potassium calcium-activated channel subfamily M regulatory beta subunit 2 (Kcnmb2), 2700049B16Rik, 3110031N04Rik, Kcmb2, KCNMB2, KCNMB3, zgc:101842

Protein level used designations for KCNMB2

  • calcium-activated potassium channel beta 2 subunit
  • potassium large conductance calcium-activated channel, subfamily M beta member 3
  • calcium-activated potassium channel subunit beta-2
  • calcium-activated potassium channel subunit beta-3
  • potassium large conductance calcium-activated channel, subfamily M, beta member 2
  • BK channel subunit beta-2
  • MaxiK channel beta 2 subunit
  • charybdotoxin receptor subunit beta-2
  • hCG1646471
  • hbeta2
  • k(VCA)beta-2
  • large conductance calcium-activated potassium channel beta 2 subunit
  • large-conductance Ca2+-activated K+ channel beta2 subunit
  • slo-beta-2
  • BKbeta2
  • calcium-activated potassium channel, subfamily M subunit beta-2
  • maxi K channel subunit beta-2
  • calcium-activated potassium channel beta 2
  • rbeta3
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