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KCNIP2 Products

(Kv Channel Interacting Protein 2 (KCNIP2))

Categories

This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified from this gene. [provided by RefSeq, Jul 2008].

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Featured KCNIP2 Categories

KCNIP2 Antibodies

High quality antibodies with extensive validation data.

KCNIP2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended KCNIP2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (6)
Cat. No. ABIN2776321
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application IHC
Validations
  • (4)
Cat. No. ABIN7456223
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application IHC
Validations
  • (4)
Cat. No. ABIN7456123
Quantity 100 μg
Datasheet Datasheet

Recommended KCNIP2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308424
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308426
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3082538
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our KCNIP2 products

Isensee, Wenzel, Buschow, Weissmann, Kuss, Hucho: "Subgroup-elimination transcriptomics identifies signaling proteins that define subclasses of TRPV1-positive neurons and a novel paracrine circuit." in: PLoS ONE, Vol. 9, Issue 12, pp. e115731, (2015) (PubMed).

You, Mao, Cai, Li, Xu: "Two novel Brugada syndrome-associated mutations increase KV4.3 membrane expression and function." in: International journal of molecular medicine, Vol. 36, Issue 1, pp. 309-15, (2015) (PubMed).

El Gebeily, El Khoury, Mathieu, Brouillette, Fiset: "Estrogen regulation of the transient outward K(+) current involves estrogen receptor α in mouse heart." in: Journal of molecular and cellular cardiology, Vol. 86, pp. 85-94, (2015) (PubMed).

Rudakova, Wagner, Frank, Volk: "Localization of Kv4.2 and KChIP2 in lipid rafts and modulation of outward K+ currents by membrane cholesterol content in rat left ventricular myocytes." in: Pflügers Archiv : European journal of physiology, Vol. 467, Issue 2, pp. 299-309, (2015) (PubMed).

Foeger, Wang, Mellor, Nerbonne: "Stabilization of Kv4 protein by the accessory K(+) channel interacting protein 2 (KChIP2) subunit is required for the generation of native myocardial fast transient outward K(+) currents." in: The Journal of physiology, Vol. 591, Issue Pt 17, pp. 4149-66, (2014) (PubMed).

Lopez-Izquierdo, Pereira, Wende, Punske, Abel, Tristani-Firouzi: "The absence of insulin signaling in the heart induces changes in potassium channel expression and ventricular repolarization." in: American journal of physiology. Heart and circulatory physiology, Vol. 306, Issue 5, pp. H747-54, (2014) (PubMed).

Lei, Zhang, Liang, Cui, Xu, Xu: "Reduced expression of IA channels is associated with postischemic seizures in hyperglycemic rats." in: Journal of neuroscience research, Vol. 92, Issue 12, pp. 1775-84, (2014) (PubMed).

Rainnie, Hazra, Dabrowska, Guo, Li, Dewitt, Muly: "Distribution and functional expression of Kv4 family ? subunits and associated KChIP ? subunits in the bed nucleus of the stria terminalis." in: The Journal of comparative neurology, Vol. 522, Issue 3, pp. 609-25, (2013) (PubMed).

Speerschneider, Grubb, Metoska, Olesen, Calloe, Thomsen: "Development of heart failure is independent of K+ channel-interacting protein 2 expression." in: The Journal of physiology, Vol. 591, Issue Pt 23, pp. 5923-37, (2013) (PubMed).

Mercer, Ma, Watts, Strome, Wohlgemuth, Yang, Cashman, Coulthart, Schmitt-Ulms, Jhamandas, Westaway: "The prion protein modulates A-type K+ currents mediated by Kv4.2 complexes through dipeptidyl aminopeptidase-like protein 6." in: The Journal of biological chemistry, Vol. 288, Issue 52, pp. 37241-55, (2013) (PubMed).

Synonyms and alternative names related to KCNIP2

potassium voltage-gated channel interacting protein 2 (KCNIP2), Kv channel-interacting protein 2 (Kcnip2), Kv channel interacting protein 2 S homeolog (kcnip2.S), potassium voltage-gated channel interacting protein 2 (Kcnip2), Kv channel interacting protein 2 (kcnip2), KCHIP2, Kchip2, KChIP2, kchip2, KCNIP2, si:ch73-173h19.2

Protein level used designations for KCNIP2

  • A-type potassium channel modulatory protein 2
  • Kv channel-interacting protein 2
  • cardiac voltage-gated potassium channel modulatory subunit
  • potassium channel-interacting protein 2
  • Kv channel interacting protein 2
  • potassium channel auxiliary subunit KCHIP2
  • Kv channel-interacting protein
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