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KCNAB1 Products

(Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 1 (KCNAB1))

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Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes three distinct isoforms which are encoded by three alternatively spliced transcript variants of this gene. These three isoforms are beta subunits, which form heteromultimeric complex with alpha subunits and modulate the activity of the pore-forming alpha subunits. [provided by RefSeq, Jul 2008].

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Featured KCNAB1 Categories

KCNAB1 Antibodies

High quality antibodies with extensive validation data.

KCNAB1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended KCNAB1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7175618
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, FACS
Validations
  • (3)
Cat. No. ABIN1498996
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (4)
  • (1)
Cat. No. ABIN1881473
Quantity 400 μL
Datasheet Datasheet

Recommended KCNAB1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6227189
Quantity 96 tests
Datasheet Datasheet

Recommended KCNAB1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308392
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3134602
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3093415
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our KCNAB1 products

Ovsepian, Steuber, Le Berre, OHara, OLeary, Dolly: "A defined heteromeric KV1 channel stabilizes the intrinsic pacemaking and regulates the output of deep cerebellar nuclear neurons to thalamic targets." in: The Journal of physiology, Vol. 591, Issue Pt 7, pp. 1771-91, (2013) (PubMed).

Tipparaju, Li, Kilfoil, Xue, Uversky, Bhatnagar, Barski: "Interactions between the C-terminus of Kv1.5 and Kv? regulate pyridine nucleotide-dependent changes in channel gating." in: Pflügers Archiv : European journal of physiology, Vol. 463, Issue 6, pp. 799-818, (2012) (PubMed).

Cheng, Yung, Covarrubias, Radice: "Cortactin is required for N-cadherin regulation of Kv1.5 channel function." in: The Journal of biological chemistry, Vol. 286, Issue 23, pp. 20478-89, (2011) (PubMed).

Decher, Gonzalez, Streit, Sachse, Renigunta, Soom, Heinemann, Daut, Sanguinetti: "Structural determinants of Kvbeta1.3-induced channel inactivation: a hairpin modulated by PIP2." in: The EMBO journal, Vol. 27, Issue 23, pp. 3164-74, (2008) (PubMed).

Cavalleri, Weale, Shianna, Singh, Lynch, Grinton, Szoeke, Murphy, Kinirons, ORourke, Ge, Depondt, Claeys, Pandolfo, Gumbs, Walley, McNamara, Mulley, Linney, Sheffield, Radtke, Tate, Chissoe et al.: "Multicentre search for genetic susceptibility loci in sporadic epilepsy syndrome and seizure types: a case-control study...." in: Lancet neurology, Vol. 6, Issue 11, pp. 970-80, (2007) (PubMed).

Lamesch, Li, Milstein, Fan, Hao, Szabo, Hu, Venkatesan, Bethel, Martin, Rogers, Lawlor, McLaren, Dricot, Borick, Cusick, Vandenhaute, Dunham, Hill, Vidal: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, (2007) (PubMed).

Suzuki, Ishihara, Sasaki, Nakagawa, Hata, Tsunoda, Watanabe, Komatsu, Ota, Isogai, Suyama, Sugano: "Statistical analysis of the 5' untranslated region of human mRNA using "Oligo-Capped" cDNA libraries." in: Genomics, Vol. 64, Issue 3, pp. 286-97, (2000) (PubMed).

Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).

Synonyms and alternative names related to KCNAB1

potassium voltage-gated channel subfamily A member regulatory beta subunit 1 (KCNAB1), potassium voltage-gated channel, shaker-related subfamily, beta member 1 a (kcnab1a), potassium voltage-gated channel, shaker-related subfamily, beta member 1 (Kcnab1), potassium voltage-gated channel subfamily A member regulatory beta subunit 1 (Kcnab1), AKR6A3, Akr8a8, hKvb3, hKvBeta3, KCNA1B, KCNAB1, KV-BETA-1, Kv-beta-1, Kvb1.3, KVBETA1, Kvbeta1.1, KvBeta3, mKv(beta)1, zgc:113627

Protein level used designations for KCNAB1

  • potassium voltage-gated channel, shaker-related subfamily, beta member 1
  • voltage-gated potassium channel subunit beta-1-like
  • voltage-gated potassium channel subunit beta-1
  • K(+) channel subunit beta-1
  • kv-beta-1
  • potassium channel Shaker beta 1 subunit cKvbeta1.1
  • putative potassim channel beta-subunit
  • potassium channel beta 3 chain
  • potassium channel beta3 subunit
  • potassium channel shaker chain beta 1a
  • potassium voltage-gated channel beta subunit
  • voltage-gated potassium channel beta-1 subunit
  • voltage-gated potassium channel shaker-related subfamily beta member 1
  • potassium voltage-gated channel shaker-related subfamily beta member 1
  • potassium channel subunit Kv beta 1
  • potassium voltage gated channel, shaker related subfamily, beta member 1
  • potassium voltage gated channel shaker related subfamily beta member 1
  • voltage-gated potassium channel beta subunit
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