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KAT2B Products

(K(lysine) Acetyltransferase 2B (KAT2B))

Categories

CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. [provided by RefSeq, Jul 2008].

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Featured KAT2B Categories

KAT2B Antibodies

High quality antibodies with extensive validation data.

KAT2B Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended KAT2B Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, FACS, ICC
Validations
  • (8)
Cat. No. ABIN7193343
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (9)
Cat. No. ABIN522308
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, RNAi
Validations
  • (6)
Cat. No. ABIN522304
Quantity 100 μg
Datasheet Datasheet

Recommended KAT2B ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Sandwich ELISA
Validations
Cat. No. ABIN421780
Quantity 96 tests
Datasheet Datasheet

Recommended KAT2B Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123658
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123657
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123659
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our KAT2B products

Sengupta, Yang, Hegde, Hegde, Mitra, Pandey, Dutta, Datarwala, Bhakat, Mitra: "Acetylation of oxidized base repair-initiating NEIL1 DNA glycosylase required for chromatin-bound repair complex formation in the human genome increases cellular resistance to oxidative stress." in: DNA repair, Vol. 66-67, pp. 1-10, (2018) (PubMed).

Xiong, Svingen, Sarmento, Smyrk, Dave, Khanna, Lomberk, Urrutia, Faubion: "Differential coupling of KLF10 to Sin3-HDAC and PCAF regulates the inducibility of the FOXP3 gene." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 307, Issue 6, pp. R608-20, (2014) (PubMed).

Cazzalini, Sommatis, Tillhon, Dutto, Bachi, Rapp, Nardo, Scovassi, Necchi, Cardoso, Stivala, Prosperi: "CBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesis." in: Nucleic acids research, Vol. 42, Issue 13, pp. 8433-48, (2014) (PubMed).

Lew, Chu, Lee, Koh, Rajasegaran, Teo, Chao: "PCAF interacts with XBP-1S and mediates XBP-1S-dependent transcription." in: Nucleic acids research, Vol. 39, Issue 2, pp. 429-39, (2011) (PubMed).

Pickard, Wong, McCance: "Acetylation of Rb by PCAF is required for nuclear localization and keratinocyte differentiation." in: Journal of cell science, Vol. 123, Issue Pt 21, pp. 3718-26, (2010) (PubMed).

Reichman, Kalathur, Lambard, Aït-Ali, Yang, Lardenois, Ripp, Poch, Zack, Sahel, Léveillard: "The homeobox gene CHX10/VSX2 regulates RdCVF promoter activity in the inner retina." in: Human molecular genetics, Vol. 19, Issue 2, pp. 250-61, (2009) (PubMed).

Tu, Prajapati, Park, Kelly, Yamamoto, Gaynor: "IKK alpha regulates estrogen-induced cell cycle progression by modulating E2F1 expression." in: The Journal of biological chemistry, Vol. 281, Issue 10, pp. 6699-706, (2006) (PubMed).

Synonyms and alternative names related to KAT2B

lysine acetyltransferase 2B (KAT2B), K(lysine) acetyltransferase 2B (kat2b), K(lysine) acetyltransferase 2A (kat2a), K(lysine) acetyltransferase 2B (Kat2b), lysine acetyltransferase 2B (Kat2b), A930006P13Rik, AI461839, AW536563, CAF, gb:dq017634, im:7156024, P, P/CAF, p/CAF, PCAF, pcaf, Pcaf, si:ch211-1j13.2, zgc:161980

Protein level used designations for KAT2B

  • p300/CBP-associated factor
  • histone acetyltransferase KAT2B
  • PCAF
  • CREBBP-associated factor
  • histone acetylase PCAF
  • histone acetyltransferase PCAF
  • lysine acetyltransferase 2B
  • K(lysine) acetyltransferase 2B
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