KARS Products
(Lysyl-tRNA Synthetase (KARS))
Categories
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured KARS Categories
KARS Antibodies
High quality antibodies with extensive validation data.
KARS ELISA Kits
Reliable ELISA kits for a wide range of species.
KARS Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended KARS Antibodies
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ABIN7268350
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ABIN969226
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Recommended KARS ELISA Kits
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ABIN6957609
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ABIN7123818
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Source
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Latest Publications for our KARS products
: "Crystal structure of tetrameric form of human lysyl-tRNA synthetase: Implications for multisynthetase complex formation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 7, pp. 2331-6, (2008) (PubMed).: "Role of HIV-1 Vpr-induced apoptosis on the release of mitochondrial lysyl-tRNA synthetase." in: FEBS letters, Vol. 581, Issue 16, pp. 3105-10, (2007) (PubMed).
: "Critical role of helix 4 of HIV-1 capsid C-terminal domain in interactions with human lysyl-tRNA synthetase." in: The Journal of biological chemistry, Vol. 282, Issue 44, pp. 32274-9, (2007) (PubMed).
: "Noncanonical function of glutamyl-prolyl-tRNA synthetase: gene-specific silencing of translation." in: Cell, Vol. 119, Issue 2, pp. 195-208, (2004) (PubMed).
: "Interaction network of human aminoacyl-tRNA synthetases and subunits of elongation factor 1 complex." in: Biochemical and biophysical research communications, Vol. 291, Issue 1, pp. 158-64, (2002) (PubMed).
: "Incorporation of lysyl-tRNA synthetase into human immunodeficiency virus type 1." in: Journal of virology, Vol. 75, Issue 11, pp. 5043-8, (2001) (PubMed).
: "The human lysyl-tRNA synthetase gene encodes both the cytoplasmic and mitochondrial enzymes by means of an unusual alternative splicing of the primary transcript." in: The Journal of biological chemistry, Vol. 275, Issue 45, pp. 35063-9, (2000) (PubMed).
Synonyms and alternative names related to KARS
Lysyl-tRNA synthetase (LysRS), lysyl-tRNA synthetase (kars), lysyl-tRNA synthetase S homeolog (kars.S), lysyl-tRNA synthetase L homeolog (kars.L), lysyl-tRNA synthetase (Bm1_16500), lysyl-tRNA synthetase (lysS), Lysyl-tRNA synthetase (lysS), lysyl-tRNA synthetase (Taci_1118), lysyl-tRNA synthetase (Tpau_1737), lysyl-tRNA synthetase (Arch_0261), lysyl-tRNA synthetase (Trad_2960), lysyl-tRNA synthetase (Spirs_3699), lysyl-tRNA synthetase (KARS), lysyl-tRNA synthetase (LOC100280510), lysyl-tRNA synthetase (Tb927.6.1510), lysyl-tRNA synthetase (Kars), AA589550, AL024334, AL033315, AL033367, cb530, CG12141, CMTRIB, D8Ertd698e, D8Wsu108e, DFNB89, Dmel\\CG12141, kars, KARS, KARS1, kars2, KARS2, KRS, krs, krs-1, LysRS, MGC53345, mKIAA0070, Tb06.28P18.190, wu:fa16h02, zgc:92483Protein level used designations for KARS
- Aats-lys-PA
- Aats-lys-PB
- Aats-lys-PC
- CG12141-PA
- CG12141-PB
- CG12141-PC
- fa16h02
- lysine--tRNA ligase
- lysyl-tRNA synthetase
- lysRS
- lysine tRNA ligase
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