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KAP1 Products

(Tripartite Motif Containing 28 (TRIM28))

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The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. [provided by RefSeq, Jul 2008].

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Featured KAP1 Categories

KAP1 Antibodies

High quality antibodies with extensive validation data.

KAP1 ELISA Kits

Reliable ELISA kits for a wide range of species.

KAP1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended KAP1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, IF, FACS
Validations
  • (1)
  • (6)
Cat. No. ABIN184913
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IP, IHC (p), ICC, ChIP
Validations
  • (4)
  • (8)
Cat. No. ABIN2855331
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (1)
  • (6)
Cat. No. ABIN2855332
Quantity 100 μL
Datasheet Datasheet

Recommended KAP1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648281
Quantity 96 tests
Datasheet Datasheet

Recommended KAP1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (2)
  • (1)
Cat. No. ABIN1323643
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1323645
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7420474
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our KAP1 products

Liu, Li, Liu, Li, Wei, Liu, Lv: "Expression and Significance of TRIM 28 in Squamous Carcinoma of Esophagus." in: Pathology oncology research : POR, Vol. 25, Issue 4, pp. 1645-1652, (2020) (PubMed).

Ochiai, Hayashi, Umeda, Yoshimura, Harada, Shimizu, Nakano, Saitoh, Liu, Yamamoto, Okamura, Ohkawa, Kimura, Nikaido: "Genome-wide kinetic properties of transcriptional bursting in mouse embryonic stem cells." in: Science advances, Vol. 6, Issue 25, pp. eaaz6699, (2020) (PubMed).

Han, Cai, Gao, Meng, Gao, Wu, Duan, Wang, Dinislam, Lin, Kang, Jiang: "Loss of ATRX suppresses ATM dependent DNA damage repair by modulating H3K9me3 to enhance temozolomide sensitivity in glioma." in: Cancer letters, Vol. 419, pp. 280-290, (2019) (PubMed).

Hung, Johnson, Chen, Byrum, Bredemeyer, Yewdell, Johnson, Lee, Deivasigamani, Hindi, Amatya, Gross, Paull, Pisapia, Chaudhuri, Petrini, Mosammaparast, Amarasinghe, Zha, Tyler, Sleckman: "MRI Is a DNA Damage Response Adaptor during Classical Non-homologous End Joining." in: Molecular cell, Vol. 71, Issue 2, pp. 332-342.e8, (2019) (PubMed).

Quek, Luff, Cheung, Kozlov, Gatei, Lee, Bellingham, Noakes, Lim, Barnett, Dingwall, Wolvetang, Mashimo, Roberts, Lavin: "Rats with a missense mutation in Atm display neuroinflammation and neurodegeneration subsequent to accumulation of cytosolic DNA following unrepaired DNA damage." in: Journal of leukocyte biology, Vol. 101, Issue 4, pp. 927-947, (2016) (PubMed).

Ding, Zhang, Wang, Wang, Fan, He, Zhang, Gao, Li, Chen: "γ-H2AX/53BP1/pKAP-1 foci and their linear tracks induced by in vitro exposure to radon and its progeny in human peripheral blood lymphocytes." in: Scientific reports, Vol. 6, pp. 38295, (2016) (PubMed).

Wang, Wolgemuth: "BET Protein BRDT Complexes With HDAC1, PRMT5, and TRIM28 and Functions in Transcriptional Repression During Spermatogenesis." in: Journal of cellular biochemistry, Vol. 117, Issue 6, pp. 1429-38, (2016) (PubMed).

Batenburg, Thompson, Hendrickson, Zhu: "Cockayne syndrome group B protein regulates DNA double-strand break repair and checkpoint activation." in: The EMBO journal, Vol. 34, Issue 10, pp. 1399-416, (2015) (PubMed).

Kijas, Lim, Bolderson, Cerosaletti, Gatei, Jakob, Tobias, Taucher-Scholz, Gueven, Oakley, Concannon, Wolvetang, Khanna, Wiesmüller, Lavin: "ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1." in: Nucleic acids research, Vol. 43, Issue 17, pp. 8352-67, (2015) (PubMed).

Hartlerode, Morgan, Wu, Buis, Ferguson: "Recruitment and activation of the ATM kinase in the absence of DNA-damage sensors." in: Nature structural & molecular biology, Vol. 22, Issue 9, pp. 736-43, (2015) (PubMed).

Synonyms and alternative names related to KAP1

tripartite motif containing 28 (TRIM28), tripartite motif containing 28 L homeolog (trim28.L), tripartite motif-containing 28 (Trim28), tripartite motif containing 28 (Trim28), AA408787, KAP-1, KAP1, kap1, Kap1, KRIP-1, Krip1, RNF96, rnf96, TF1B, tf1b, TIF1B, tif1b, Tif1b, Tif1beta, TIF1BETA, TRIM28

Protein level used designations for KAP1

  • E3 SUMO-protein ligase TRIM28
  • KAP-1
  • KRAB-associated protein 1
  • KRAB-interacting protein 1
  • KRIP-1
  • RING finger protein 96
  • TIF1-beta
  • nuclear corepressor KAP-1
  • transcription intermediary factor 1-beta
  • transcriptional intermediary factor 1-beta
  • tripartite motif-containing 28
  • tripartite motif-containing protein 28
  • transcription intermediary factor 1-beta-like
  • KRAB-A-interacting protein
  • transcriptional intermediary factor 1, beta
  • tripartite motif protein 28
  • TIF1beta transcription factor
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