Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Kallikrein 7 Products

(Kallikrein 7 (KLK7))

Categories

This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured Kallikrein 7 Categories

Kallikrein 7 Antibodies

High quality antibodies with extensive validation data.

Kallikrein 7 ELISA Kits

Reliable ELISA kits for a wide range of species.

Kallikrein 7 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Kallikrein 7 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN652197
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (3)
Cat. No. ABIN652198
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (1)
  • (2)
Cat. No. ABIN2855653
Quantity 100 μL
Datasheet Datasheet

Recommended Kallikrein 7 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6957256
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962041
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957257
Quantity 96 tests
Datasheet Datasheet

Recommended Kallikrein 7 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308870
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320700
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308869
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our Kallikrein 7 products

Delaunay, Deschamps, Haddada, Walker, Soosaipillai, Soualmia, El Amri, Diamandis, Brattsand, Magdolen, Darmoul: "Aberrant expression of kallikrein-related peptidase 7 is correlated with human melanoma aggressiveness by stimulating cell migration and invasion." in: Molecular oncology, Vol. 11, Issue 10, pp. 1330-1347, (2018) (PubMed).

Sheets, Massey, Cronk, Iafrati, Herman: "Matrix- and plasma-derived peptides promote tissue-specific injury responses and wound healing in diabetic swine." in: Journal of translational medicine, Vol. 14, Issue 1, pp. 197, (2016) (PubMed).

McGovern, Meinert, de Veer, Hollier, Parker, Upton: "Attenuated kallikrein-related peptidase activity disrupts desquamation and leads to stratum corneum thickening in human skin equivalent models." in: The British journal of dermatology, (2016) (PubMed).

Yu, Prassas, Dimitromanolakis, Diamandis: "Novel Biological Substrates of Human Kallikrein 7 Identified through Degradomics." in: The Journal of biological chemistry, Vol. 290, Issue 29, pp. 17762-75, (2015) (PubMed).

Yamamoto, Yamamoto, Yamada, Hasegawa, Hongo, Oda, Amizuka: "Hertwig's epithelial root sheath cell behavior during initial acellular cementogenesis in rat molars." in: Histochemistry and cell biology, Vol. 142, Issue 5, pp. 489-96, (2014) (PubMed).

Heiker, Klöting, Kovacs, Kuettner, Sträter, Schultz, Kern, Stumvoll, Blüher, Beck-Sickinger: "Vaspin inhibits kallikrein 7 by serpin mechanism." in: Cellular and molecular life sciences : CMLS, Vol. 70, Issue 14, pp. 2569-83, (2013) (PubMed).

Ishida-Yamamoto, Deraison, Bonnart, Bitoun, Robinson, OBrien, Wakamatsu, Ohtsubo, Takahashi, Hashimoto, Dopping-Hepenstal, McGrath, Iizuka, Richard, Hovnanian: "LEKTI is localized in lamellar granules, separated from KLK5 and KLK7, and is secreted in the extracellular spaces of the superficial stratum granulosum." in: The Journal of investigative dermatology, Vol. 124, Issue 2, pp. 360-6, (2005) (PubMed).

Planque, de Monte, Guyetant, Rollin, Desmazes, Panel, Lemarié, Courty: "KLK5 and KLK7, two members of the human tissue kallikrein family, are differentially expressed in lung cancer." in: Biochemical and biophysical research communications, Vol. 329, Issue 4, pp. 1260-6, (2005) (PubMed).

Vasilopoulos, Cork, Murphy, Williams, Robinson, Duff, Ward, Tazi-Ahnini: "Genetic association between an AACC insertion in the 3'UTR of the stratum corneum chymotryptic enzyme gene and atopic dermatitis." in: The Journal of investigative dermatology, Vol. 123, Issue 1, pp. 62-6, (2004) (PubMed).

Sumer, Ahmad, Al-Mouzan, Al-Awamy: "Interaction of alpha-thalassemia with other hemoglobinopathies in the eastern province of Saudi Arabia." in: Birth defects original article series, Vol. 23, Issue 5A, pp. 343-7, (1988) (PubMed).

Synonyms and alternative names related to Kallikrein 7

kallikrein related-peptidase 7 (chymotryptic, stratum corneum) (Klk7), kallikrein-related peptidase 7 (Klk7), kallikrein related peptidase 7 (KLK7), kallikrein related peptidase 7 (Klk7), hK7, Prss6, PRSS6, SCCE

Protein level used designations for Kallikrein 7

  • kallikrein 7 (chymotryptic, stratum corneum)
  • kallikrein-7
  • protease, serine, 6
  • serine protease 6
  • stratum corneum chymotryptic enzyme
  • thymopsin
  • kallikrein related-peptidase 7 (chymotryptic, stratum corneum)
  • signal protein
You are here:
Support