Kallikrein 5 Products
(Kallikrein 5 (KLK5))
Categories
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008].
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Featured Kallikrein 5 Categories
Kallikrein 5 Antibodies
High quality antibodies with extensive validation data.
Kallikrein 5 ELISA Kits
Reliable ELISA kits for a wide range of species.
Kallikrein 5 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Kallikrein 5 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB
Validations
- (1)
- (2)
Cat. No.
ABIN390305
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7431812
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7157213
Quantity
100 μg
Datasheet
Datasheet
Recommended Kallikrein 5 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957250
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957251
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6976005
Quantity
96 tests
Datasheet
Datasheet
Recommended Kallikrein 5 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275095
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275097
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308863
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our Kallikrein 5 products
: "PRSS3/Mesotrypsin and kallikrein-related peptidase 5 are associated with poor prognosis and contribute to tumor cell invasion and growth in lung adenocarcinoma." in: Scientific reports, Vol. 9, Issue 1, pp. 1844, (2019) (PubMed).: "Loss of ceramide synthase 3 causes lethal skin barrier disruption." in: Human molecular genetics, Vol. 21, Issue 3, pp. 586-608, (2012) (PubMed).
: "Kallikrein-5 promotes cleavage of desmoglein-1 and loss of cell-cell cohesion in oral squamous cell carcinoma." in: The Journal of biological chemistry, Vol. 286, Issue 11, pp. 9127-35, (2011) (PubMed).
: "Human tissue kallikrein 5 is a member of a proteolytic cascade pathway involved in seminal clot liquefaction and potentially in prostate cancer progression." in: The Journal of biological chemistry, Vol. 281, Issue 18, pp. 12743-50, (2006) (PubMed).
: "LEKTI is localized in lamellar granules, separated from KLK5 and KLK7, and is secreted in the extracellular spaces of the superficial stratum granulosum." in: The Journal of investigative dermatology, Vol. 124, Issue 2, pp. 360-6, (2005) (PubMed).
: "Biochemical and enzymatic characterization of human kallikrein 5 (hK5), a novel serine protease potentially involved in cancer progression." in: The Journal of biological chemistry, Vol. 280, Issue 15, pp. 14628-35, (2005) (PubMed).
: "KLK5 and KLK7, two members of the human tissue kallikrein family, are differentially expressed in lung cancer." in: Biochemical and biophysical research communications, Vol. 329, Issue 4, pp. 1260-6, (2005) (PubMed).
Synonyms and alternative names related to Kallikrein 5
kallikrein related peptidase 5 (KLK5), kallikrein related-peptidase 5 (Klk5), kallikrein 5-like (Klk5l), 1110030O19Rik, KAL, KALA, KLK-L2, Klk1, Klk5, KLKL2, RATKALA, SCTEProtein level used designations for Kallikrein 5
- kallikrein 5
- kallikrein-5
- kallikrein-like protein 2
- stratum corneum tryptic enzyme
- Kallikrein 1 renal/pancreas/salivary
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