JNK Products
(Mitogen-Activated Protein Kinase 8 (MAPK8))
Categories
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
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Featured JNK Categories
JNK Antibodies
High quality antibodies with extensive validation data.
JNK ELISA Kits
Reliable ELISA kits for a wide range of species.
JNK Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended JNK Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (4)
- (8)
Cat. No.
ABIN3020887
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Human, Mouse, Rabbit, Rat
Application
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), ICC, IHC (fro)
Validations
- (16)
- (4)
Cat. No.
ABIN732368
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Pig, Rat
Application
WB, ELISA, IF, ICC
Validations
- (3)
- (5)
Cat. No.
ABIN6262710
Quantity
100 μL
Datasheet
Datasheet
Recommended JNK ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Cell ELISA
Validations
- (4)
- (6)
Cat. No.
ABIN1981833
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968648
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
- (2)
Cat. No.
ABIN2748302
Quantity
96 tests
Datasheet
Datasheet
Recommended JNK Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1310303
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123994
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123995
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our JNK products
: "MiR-377 promotes white adipose tissue inflammation and decreases insulin sensitivity in obesity via suppression of sirtuin-1 (SIRT1)." in: Oncotarget, Vol. 8, Issue 41, pp. 70550-70563, (2018) (PubMed).: "Dysifragilone A inhibits LPS‑induced RAW264.7 macrophage activation by blocking the p38 MAPK signaling pathway." in: Molecular medicine reports, Vol. 17, Issue 1, pp. 674-682, (2018) (PubMed).
: "Trimethylamine N-oxide promotes atherosclerosis via CD36-dependent MAPK/JNK pathway." in: Biomedicine & pharmacotherapy, Vol. 97, pp. 941-947, (2018) (PubMed).
: "Neuroprotective Effect of Modified Xijiao Dihuang Decoction against Oxygen-Glucose Deprivation and Reoxygenation-Induced Injury in PC12 Cells: Involvement of TLR4-MyD88/NF-κB Signaling Pathway." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2017, pp. 3848595, (2018) (PubMed).
: "The p75 neurotrophin receptor might mediate sepsis-induced synaptic and cognitive impairments." in: Behavioural brain research, Vol. 347, pp. 339-349, (2018) (PubMed).
: "Ferroptosis is newly characterized form of neuronal cell death in response to arsenite exposure." in: Neurotoxicology, Vol. 67, pp. 27-36, (2018) (PubMed).
: "Anti-inflammatory action of ambuic acid, a natural product isolated from the solid culture of Pestalotiopsis neglecta, through blocking ERK/JNK mitogen-activated protein kinase signaling pathway." in: Experimental and therapeutic medicine, Vol. 16, Issue 2, pp. 1538-1546, (2018) (PubMed).
: "Glucocorticoid mediates prenatal caffeine exposure-induced endochondral ossification retardation and its molecular mechanism in female fetal rats." in: Cell death & disease, Vol. 8, Issue 10, pp. e3157, (2018) (PubMed).
: "Pseudolaric acid B induced autophagy, but not apoptosis, in MRC5 human fibroblast cells." in: Oncology letters, Vol. 15, Issue 1, pp. 863-870, (2018) (PubMed).
: "p21-Activated Kinase 4 Signaling Promotes Japanese Encephalitis Virus-Mediated Inflammation in Astrocytes." in: Frontiers in cellular and infection microbiology, Vol. 7, pp. 271, (2018) (PubMed).
Synonyms and alternative names related to JNK
mitogen-activated protein kinase 8 (MAPK8), Stress-activated protein kinase jnk-1 (jnk-1), mitogen-activated protein kinase 8 (Mapk8), basket (bsk), Protein kinase superfamily protein (ATMPK8), mitogen-activated protein kinase 8 L homeolog (mapk8.L), mitogen-activated protein kinase 8b (mapk8b), mitogen-activated protein kinase 8B-like (LOC109094263), AI849689, BSK, Bsk, BSK/DJNK, c-Jun, CG5680, D-JNK, D-junk, DBSK/JNK, DJNK, dJNK, DJNK/bsk, Dmel\\CG5680, JNK, Jnk, jnk, JNK-46, JNK/SAPK, JNK1, jnk1, JNK1A2, JNK21B1/2, JNKb, Junk, mapk8, mapk8b, PRKM8, Prkm8, SAPK1, sapk1, SAPK1c, SAPKa, T10F20.15, zgc:112379Protein level used designations for JNK
- JUN N-terminal kinase
- MAP kinase 8
- c-Jun N-terminal kinase 1
- mitogen-activated protein kinase 8 isoform JNK1 alpha1
- mitogen-activated protein kinase 8 isoform JNK1 beta2
- stress-activated protein kinase 1
- stress-activated protein kinase 1c
- JNK1 beta1 protein kinase
- MAPK 8
- mitogen activated protein kinase 8
- protein kinase mitogen-activated 8
- stress-activated protein kinase JNK1
- SAPK gamma
- c-jun NH2-terminal kinase
- p54 gamma
- CG5680-PB
- CG5680-PE
- CG5680-PF
- JNK
- JUN kinase
- Jun N-terminal kinase
- Jun NH2-terminal kinase
- Jun-N-terminal kinase
- Jun-kinase
- bsk-PB
- bsk-PE
- bsk-PF
- c-Jun N-terminal kinase
- c-Jun aminoterminal kinase
- c-Jun-N-terminal kinase
- drosophila JNK
- janus kinase 1
- jnk1a-1
- mitogen-activated protein kinase 8
- LOW QUALITY PROTEIN: mitogen-activated protein kinase 8B-like
- MAP kinase 8B
- MAPK 8B
- Mitogen-activated protein kinase 8B
- Stress-activated protein kinase JNKb
- c-Jun N-terminal kinase B
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