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JARID2 Products

(Jumonji, AT Rich Interactive Domain 2 (JARID2))

Categories

This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies. [provided by RefSeq, May 2012].

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Featured JARID2 Categories

JARID2 Antibodies

High quality antibodies with extensive validation data.

JARID2 ELISA Kits

Reliable ELISA kits for a wide range of species.

JARID2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended JARID2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, ICC, FACS
Validations
  • (5)
Cat. No. ABIN5542458
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7165672
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN561570
Quantity 50 μL
Datasheet Datasheet

Recommended JARID2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1151728
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1151727
Quantity 96 tests
Datasheet Datasheet
Reactivity Chicken
Analytical Method
Validations
Cat. No. ABIN1151726
Quantity 96 tests
Datasheet Datasheet

Recommended JARID2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308286
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3093203
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3135541
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our JARID2 products

Kumar, Evans: "Activation-Induced Cytidine Deaminase Regulates Fibroblast Growth Factor/Extracellular Signal-Regulated Kinases Signaling to Achieve the Naïve Pluripotent State During Reprogramming." in: Stem cells (Dayton, Ohio), Vol. 37, Issue 8, pp. 1003-1017, (2019) (PubMed).

Perino, van Mierlo, Karemaker, van Genesen, Vermeulen, Marks, van Heeringen, Veenstra: "MTF2 recruits Polycomb Repressive Complex 2 by helical-shape-selective DNA binding." in: Nature genetics, Vol. 50, Issue 7, pp. 1002-1010, (2018) (PubMed).

Jin, Oda, Chen, Yang, Zhou, Kang, Valentine, Kefauver, Liao, Zhang, Gonzalez-Martin, Shepherd, Morgan, Mondala, Head, Kim, Xiao, Fu, Liu, Han, Williamson, Xiao: "Differential Sensitivity of Target Genes to Translational Repression by miR-17~92." in: PLoS genetics, Vol. 13, Issue 2, pp. e1006623, (2017) (PubMed).

Qu, Yang, Liu, Shi, Ji, Li, Hou: "c-Myc is Required for BRAF(V600E)-Induced Epigenetic Silencing by H3K27me3 in Tumorigenesis." in: Theranostics, Vol. 7, Issue 7, pp. 2092-2107, (2017) (PubMed).

Schneider, Staffas, Röhner, Malmberg, Ashouri, Krowiorz, Pochert, Miller, Wei, Arabanian, Buske, Döhner, Bullinger, Fogelstrand, Heuser, Döhner, Xiang, Ruschmann, Petriv, Heravi-Moussavi, Hansen et al.: "Micro-ribonucleic acid-155 is a direct target of Meis1, but not a driver in acute myeloid leukemia. ..." in: Haematologica, Vol. 103, Issue 2, pp. 246-255, (2017) (PubMed).

Fantini, Huang, Asara, Bagchi, Raychaudhuri: "Chromatin association of XRCC5/6 in the absence of DNA damage depends on the XPE gene product DDB2." in: Molecular biology of the cell, Vol. 28, Issue 1, pp. 192-200, (2016) (PubMed).

Cooper, Grijzenhout, Underwood, Ancelin, Zhang, Nesterova, Anil-Kirmizitas, Bassett, Kooistra, Agger, Helin, Heard, Brockdorff: "Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2." in: Nature communications, Vol. 7, pp. 13661, (2016) (PubMed).

Yoon, Foley, Baker: "HEB associates with PRC2 and SMAD2/3 to regulate developmental fates." in: Nature communications, Vol. 6, pp. 6546, (2015) (PubMed).

Pereira, Martinez, Engel, Cruz-Guilloty, Barboza, Tsagaratou, Lio, Berg, Lee, Kronenberg, Bandukwala, Rao: "Jarid2 is induced by TCR signalling and controls iNKT cell maturation." in: Nature communications, Vol. 5, pp. 4540, (2014) (PubMed).

Tange, Oktyabri, Terashima, Ishimura, Suzuki: "JARID2 is involved in transforming growth factor-beta-induced epithelial-mesenchymal transition of lung and colon cancer cell lines." in: PLoS ONE, Vol. 9, Issue 12, pp. e115684, (2014) (PubMed).

Synonyms and alternative names related to JARID2

jumonji and AT-rich interaction domain containing 2 (JARID2), jumonji, AT rich interactive domain 2 (Jarid2), jumonji, AT rich interactive domain 2a (jarid2a), jumonji and AT-rich interaction domain containing 2 (jarid2), jumonji and AT-rich interaction domain containing 2 (Jarid2), jumonji, AT rich interactive domain 2b (jarid2b), jumonji and AT-rich interaction domain containing 2 L homeolog (jarid2.L), JARID2, jarid2, jarid2-a, jarid2-b, jarid2.S, jarid2b, JMJ, Jmj, jmj, jumonji, Jumonji, si:dkey-211c3.1

Protein level used designations for JARID2

  • jumonji homolog
  • jumonji-like protein
  • jumonji/ARID domain-containing protein 2
  • protein Jumonji
  • jumonji, AT rich interactive domain 2 protein
  • jumonji, AT rich interactive domain 2
  • protein Jumonji-like
  • jumonji and AT-rich interaction domain containing 2 L homeolog
  • jumonji and AT-rich interaction domain containing 2 S homeolog
  • jumonji, AT rich interactive domain 2 b
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