JAM3 Products
(Junctional Adhesion Molecule 3 (JAM3))
Categories
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. A mutation in an intron of this gene is associated with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011].
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Featured JAM3 Categories
JAM3 Antibodies
High quality antibodies with extensive validation data.
JAM3 ELISA Kits
Reliable ELISA kits for a wide range of species.
JAM3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended JAM3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
Cat. No.
ABIN7157174
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (3)
Cat. No.
ABIN529476
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (fro), IF (cc), IF (p), IHC (p), ICC
Validations
- (2)
Cat. No.
ABIN1386406
Quantity
100 μL
Datasheet
Datasheet
Recommended JAM3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957242
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN2703277
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6384741
Quantity
96 tests
Datasheet
Datasheet
Recommended JAM3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123655
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308282
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7320269
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our JAM3 products
: "Functional capacities of human IgM memory B cells in early inflammatory responses and secondary germinal center reactions." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 6, pp. E546-55, (2015) (PubMed).: "Function of Jam-B/Jam-C interaction in homing and mobilization of human and mouse hematopoietic stem and progenitor cells." in: Stem cells (Dayton, Ohio), Vol. 32, Issue 4, pp. 1043-54, (2015) (PubMed).
: "Constitutive and functionally relevant expression of JAM-C on platelets." in: Thrombosis and haemostasis, Vol. 103, Issue 4, pp. 857-9, (2010) (PubMed).
: "Junctional adhesion molecule (JAM)-B supports lymphocyte rolling and adhesion through interaction with alpha4beta1 integrin." in: Immunology, Vol. 128, Issue 2, pp. 196-205, (2009) (PubMed).
: "Expression of junctional adhesion molecules on the human lymphatic endothelium." in: Microvascular research, Vol. 75, Issue 2, pp. 269-78, (2008) (PubMed).
: "Expression profiling of microdissected cell populations selected from basal cells in normal epidermis and basal cell carcinoma." in: The British journal of dermatology, Vol. 158, Issue 3, pp. 527-38, (2008) (PubMed).
: "Junctional adhesion molecule-C promotes metastatic potential of HT1080 human fibrosarcoma." in: The Journal of biological chemistry, Vol. 282, Issue 11, pp. 8276-83, (2007) (PubMed).
: "JAM-C is a component of desmosomes and a ligand for CD11b/CD18-mediated neutrophil transepithelial migration." in: Molecular biology of the cell, Vol. 15, Issue 8, pp. 3926-37, (2004) (PubMed).
: "The junctional adhesion molecule 3 (JAM-3) on human platelets is a counterreceptor for the leukocyte integrin Mac-1." in: The Journal of experimental medicine, Vol. 196, Issue 5, pp. 679-91, (2002) (PubMed).
: "Narrowing the critical region within 11q24-qter for hypoplastic left heart and identification of a candidate gene, JAM3, expressed during cardiogenesis." in: Genomics, Vol. 79, Issue 4, pp. 475-8, (2002) (PubMed).
Synonyms and alternative names related to JAM3
junctional adhesion molecule 3 (JAM3), junctional adhesion molecule 3b (jam3b), junctional adhesion molecule 3a (jam3a), junction adhesion molecule 3 (Jam3), junctional adhesion molecule 3 (Jam3), 1110002N23Rik, JAM-2, JAM-3, JAM-C, JAM3, jam3, JAMC, jamc.2, Jcam3, sr:nyz155, wu:fb30h11, wu:fc08c06, wu:fc13e04, wu:fc25g11Protein level used designations for JAM3
- junctional adhesion molecule 3
- jamc
- jamc.1
- si:ch211-277g22.3
- JAM-C-like protein
- junction cell adhesion molecule 3
- junction cell adhesion molecule C
- junctional adhesion molecule C
- JAM-3
- JAM-C
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