JAK3 Products
(Janus Kinase 3 (JAK3))
Categories
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008].
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Featured JAK3 Categories
JAK3 Antibodies
High quality antibodies with extensive validation data.
JAK3 ELISA Kits
Reliable ELISA kits for a wide range of species.
JAK3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended JAK3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7439474
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, FACS, ICC
Validations
- (1)
- (4)
Cat. No.
ABIN969224
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (1)
- (2)
Cat. No.
ABIN681013
Quantity
100 μL
Datasheet
Datasheet
Recommended JAK3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968078
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968077
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957233
Quantity
96 tests
Datasheet
Datasheet
Recommended JAK3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308278
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN5508976
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7398455
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our JAK3 products
: "Combination of gemcitabine and erlotinib inhibits recurrent pancreatic cancer growth in mice via the JAK-STAT pathway." in: Oncology reports, Vol. 39, Issue 3, pp. 1081-1089, (2018) (PubMed).: "Jak3 is involved in CCR7-dependent migration and invasion in metastatic squamous cell carcinoma of the head and neck." in: Oncology letters, Vol. 13, Issue 5, pp. 3191-3197, (2017) (PubMed).
: "Direct regulation of IL-2 by curcumin." in: Biochemical and biophysical research communications, Vol. 495, Issue 1, pp. 300-305, (2017) (PubMed).
: "JAK3 as an Emerging Target for Topical Treatment of Inflammatory Skin Diseases." in: PloS one, Vol. 11, Issue 10, pp. e0164080, (2017) (PubMed).
: "Novel compound heterozygous mutations in a Japanese girl with Janus kinase 3 deficiency." in: Pediatrics international : official journal of the Japan Pediatric Society, Vol. 58, Issue 10, pp. 1076-1080, (2016) (PubMed).
: "MSX3 Switches Microglia Polarization and Protects from Inflammation-Induced Demyelination." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 16, pp. 6350-65, (2015) (PubMed).
: "Inhibition of STAT3 activation by KT-18618 via the disruption of the interaction between JAK3 and STAT3." in: Biochemical pharmacology, Vol. 89, Issue 1, pp. 62-73, (2014) (PubMed).
: "Jak3 expression and genomic sequence in pediatric acute lymphoblastic leukemia." in: Leukemia & lymphoma, Vol. 43, Issue 12, pp. 2355-62, (2003) (PubMed).
: "MAPKs: new JNK expands the group." in: Trends in biochemical sciences, Vol. 19, Issue 11, pp. 470-3, (1995) (PubMed).
Synonyms and alternative names related to JAK3
Janus kinase 3 (JAK3), Janus kinase 3 (Jak3), fae, JAK, JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK, RATJAK3, wilProtein level used designations for JAK3
- Janus kinase 3 (a protein tyrosine kinase, leukocyte)
- leukocyte Janus kinase
- tyrosine-protein kinase JAK3
- JAK-3
- Janus kinase 3 protein-tyrosine kinase
- Janus kinase 3, protein-tyrosine kinase
- Janus tyrosine kinase
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