ITK Products
(IL2-Inducible T-Cell Kinase (ITK))
Categories
This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. [provided by RefSeq, Jul 2008].
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Featured ITK Categories
ITK Antibodies
High quality antibodies with extensive validation data.
ITK ELISA Kits
Reliable ELISA kits for a wide range of species.
ITK Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ITK Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Rat
Application
WB, ELISA, IHC, IF, FACS
Validations
- (6)
Cat. No.
ABIN1589997
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, ICC, FACS
Validations
- (2)
- (5)
Cat. No.
ABIN969222
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (5)
Cat. No.
ABIN184605
Quantity
100 μg
Datasheet
Datasheet
Recommended ITK ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956705
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4886150
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5655254
Quantity
96 tests
Datasheet
Datasheet
Recommended ITK Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123402
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308233
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308231
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our ITK products
: "Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation." in: The Journal of clinical investigation, Vol. 119, Issue 5, pp. 1350-8, (2009) (PubMed).: "Tacrolimus differentially regulates the proliferation of conventional and regulatory CD4(+) T cells." in: Molecules and cells, Vol. 28, Issue 2, pp. 125-30, (2009) (PubMed).
: "Association of atopy and eczema with polymorphisms in T-cell immunoglobulin domain and mucin domain-IL-2-inducible T-cell kinase gene cluster in chromosome 5 q 33." in: The Journal of allergy and clinical immunology, Vol. 116, Issue 3, pp. 650-6, (2005) (PubMed).
: "Itk phosphorylation sites are required for functional activity in primary T cells." in: The Journal of biological chemistry, Vol. 278, Issue 39, pp. 37112-21, (2003) (PubMed).
: "Regulation of the tyrosine kinase Itk by the peptidyl-prolyl isomerase cyclophilin A." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 4, pp. 1899-904, (2002) (PubMed).
: "Nuclear localization of the tyrosine kinase Itk and interaction of its SH3 domain with karyopherin alpha (Rch1alpha)." in: International immunology, Vol. 13, Issue 10, pp. 1265-74, (2001) (PubMed).
: "Characterization of Itk tyrosine kinase: contribution of noncatalytic domains to enzymatic activity." in: Protein expression and purification, Vol. 22, Issue 2, pp. 211-9, (2001) (PubMed).
: "Regulated association between the tyrosine kinase Emt/Itk/Tsk and phospholipase-C gamma 1 in human T lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 12, pp. 6435-41, (2000) (PubMed).
: "Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade." in: The Journal of biological chemistry, Vol. 275, Issue 3, pp. 2219-30, (2000) (PubMed).
: "Rapid movements of vimentin on microtubule tracks: kinesin-dependent assembly of intermediate filament networks." in: The Journal of cell biology, Vol. 143, Issue 1, pp. 159-70, (1998) (PubMed).
Synonyms and alternative names related to ITK
IL2 inducible T cell kinase (Itk), IL2 inducible T-cell kinase (ITK), IL2-inducible T-cell kinase (Itk), Emt, EMT, LPFS1, LYK, PSCTK2, Tcsk, TskProtein level used designations for ITK
- T-cell-specific kinase
- interleukin-2-inducible T cell kinase
- kinase TLK
- tyrosine-protein kinase ITK/TSK
- IL-2-inducible T cell kinase
- IL-2-inducible T-cell kinase
- homolog of mouse T-cell itk/tsk
- interleukin-2-inducible T-cell kinase
- kinase EMT
- tyrosine-protein kinase LYK
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