ITGA8 Products
(Integrin alpha-8 (ITGA8))
Categories
Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and regulates neurite outgrowth of sensory and motor neurons.
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Featured ITGA8 Categories
ITGA8 Antibodies
High quality antibodies with extensive validation data.
ITGA8 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ITGA8 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN655529
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (2)
Cat. No.
ABIN521957
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7443512
Quantity
100 μL
Datasheet
Datasheet
Recommended ITGA8 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308173
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7416829
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2723529
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our ITGA8 products
: "Reconstitution of the embryonic kidney identifies a donor cell contribution to the renal vasculature upon transplantation." in: Scientific reports, Vol. 9, Issue 1, pp. 1172, (2019) (PubMed).: "Cellular entry and uncoating of naked and quasi-enveloped human hepatoviruses." in: eLife, Vol. 8, (2019) (PubMed).
: "Role of integrin alpha8 in murine model of lung fibrosis." in: PLoS ONE, Vol. 13, Issue 5, pp. e0197937, (2018) (PubMed).
: "Enteric Species F Human Adenoviruses use Laminin-Binding Integrins as Co-Receptors for Infection of Ht-29 Cells." in: Scientific reports, Vol. 8, Issue 1, pp. 10019, (2018) (PubMed).
: "Regenerative potential of induced pluripotent stem cells derived from patients undergoing haemodialysis in kidney regeneration." in: Scientific reports, Vol. 8, Issue 1, pp. 14919, (2018) (PubMed).
: "Aberrant DNA methylation of Tgfb1 in diabetic kidney mesangial cells." in: Scientific reports, Vol. 8, Issue 1, pp. 16338, (2018) (PubMed).
: "X-Linked Alport Dogs Demonstrate Mesangial Filopodial Invasion of the Capillary Tuft as an Early Event in Glomerular Damage." in: PLoS ONE, Vol. 11, Issue 12, pp. e0168343, (2017) (PubMed).
: "Dependence of Glomerulonephritis Induction on Novel Intraglomerular Alternatively Activated Bone Marrow-Derived Macrophages and Mac-1 and PD-L1 in Lupus-Prone NZM2328 Mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 198, Issue 7, pp. 2589-2601, (2017) (PubMed).
: "Activation of Hypoxia Signaling in Stromal Progenitors Impairs Kidney Development." in: The American journal of pathology, Vol. 187, Issue 7, pp. 1496-1511, (2017) (PubMed).
: "Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development." in: Developmental cell, Vol. 41, Issue 4, pp. 349-365.e3, (2017) (PubMed).
Synonyms and alternative names related to ITGA8
integrin alpha 8 (Itga8), integrin subunit alpha 8 (ITGA8), integrin subunit alpha 8 (Itga8), AI447669, RGD1564327Protein level used designations for ITGA8
- integrin alpha-8
- integrin alpha 8 subunit
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