ITGA2 Products
(Integrin alpha 2 (ITGA2))
Categories
This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012].
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Featured ITGA2 Categories
ITGA2 Antibodies
High quality antibodies with extensive validation data.
ITGA2 ELISA Kits
Reliable ELISA kits for a wide range of species.
ITGA2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ITGA2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
FACS, ELISA, ICC
Validations
- (5)
Cat. No.
ABIN5684082
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (1)
- (4)
Cat. No.
ABIN561540
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7433282
Quantity
100 μL
Datasheet
Datasheet
Recommended ITGA2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (6)
Cat. No.
ABIN6720453
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956838
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6973617
Quantity
96 tests
Datasheet
Datasheet
Recommended ITGA2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7490739
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308165
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7401443
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our ITGA2 products
: "Integrin αvβ1 Modulation Affects Subtype B Avian Metapneumovirus Fusion Protein-mediated Cell-Cell Fusion and Virus Infection." in: The Journal of biological chemistry, Vol. 291, Issue 28, pp. 14815-25, (2016) (PubMed).: "Glycosylation modulates melanoma cell α2β1 and α3β1 integrin interactions with type IV collagen." in: The Journal of biological chemistry, Vol. 289, Issue 31, pp. 21591-604, (2014) (PubMed).
: "Cultivation and characterization of cornea limbal epithelial stem cells on lens capsule in animal material-free medium." in: PLoS ONE, Vol. 7, Issue 10, pp. e47187, (2012) (PubMed).
: "Identification and characterization of the integrin alpha2beta1 binding motif in chondroadherin mediating cell attachment." in: The Journal of biological chemistry, Vol. 286, Issue 5, pp. 3925-34, (2011) (PubMed).
: "Evaluation of the frequency of putative prostate cancer stem cells in primary and metastatic prostate cancer." in: The Prostate, Vol. 70, Issue 8, pp. 875-82, (2010) (PubMed).
: "Establishment and characterization of novel human uterine leiomyosarcoma cell lines." in: International journal of oncology, Vol. 37, Issue 1, pp. 125-31, (2010) (PubMed).
: "Indoleamine 2,3-dioxygenase promotes peritoneal dissemination of ovarian cancer through inhibition of natural killercell function and angiogenesis promotion." in: International journal of oncology, Vol. 38, Issue 1, pp. 113-20, (2010) (PubMed).
: "Remodeling of the human endometrial epithelium is regulated by laminin and type IV collagen." in: International journal of molecular medicine, Vol. 23, Issue 2, pp. 173-80, (2009) (PubMed).
: "Differential IL-23 requirement for IL-22 and IL-17A production during innate immunity against Salmonella enterica serovar Enteritidis." in: International immunology, Vol. 21, Issue 5, pp. 555-65, (2009) (PubMed).
: "Combined immunogene therapy of IL-6 and IL-15 enhances anti-tumor activity through augmented NK cytotoxicity." in: Cancer letters, Vol. 272, Issue 2, pp. 285-95, (2008) (PubMed).
Synonyms and alternative names related to ITGA2
integrin subunit alpha 2 (ITGA2), integrin alpha 2 (Itga2), integrin subunit alpha 2 (Itga2), BR, CD49B, DX5, GPIa, HPA-5, VLA-2, VLAA2Protein level used designations for ITGA2
- CD49 antigen-like family member B
- VLA2 receptor, alpha-2 subunit
- collagen receptor
- human platelet alloantigen system 5
- integrin alpha-2
- platelet antigen Br
- platelet glycoprotein GPIa
- platelet membrane glycoprotein Ia
- very late activation protein 2 receptor, alpha-2 subunit
- GPIa
- VLA-2 receptor, alpha 2 subunit
- VLA-2 subunit alpha
- VLA-2 alpha chain
- LOW QUALITY PROTEIN: integrin alpha-2
- integrin alpha 2 subunit
- integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
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