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- Target See all IgG1 products
- IgG1
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Host
- Mouse
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Clonality
- Monoclonal
- Application
- Isotype Control (IsoC), ELISA, Western Blotting (WB)
- Characteristics
- Concentration Definition: by UV absorbance at 280 nm
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Clone
- MG1L
- Isotype
- IgG1
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- Application Notes
- Mouse IgG1 lambda isotype control can be utilized as a control or standard reagent in Western Blotting and ELISA experiments where determination of sample isotype is important.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Preservative
- Sodium azide
- Precaution of Use
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- Handling Advice
- Monoclonal antibodies should not be stored at a temperature below -25 °C due to the aggregation effect of the protein.
- Storage
- 4 °C
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Binding of Candida albicans to Human CEACAM1 and CEACAM6 Modulates the Inflammatory Response of Intestinal Epithelial Cells." in: mBio, Vol. 8, Issue 2, (2017) (PubMed).
: "
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Binding of Candida albicans to Human CEACAM1 and CEACAM6 Modulates the Inflammatory Response of Intestinal Epithelial Cells." in: mBio, Vol. 8, Issue 2, (2017) (PubMed).
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- Target
- IgG1
- Abstract
- IgG1 Products
- Synonyms
- IgG1 Isotype Control, Igh-4 Isotype Control, VH7183 Isotype Control, immunoglobulin heavy constant gamma 1 (G1m marker) Isotype Control, Ighg1 Isotype Control
- Target Type
- Antibody
- Background
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Secreted as part of the adaptive immune response by plasma B cells, mouse immunoglobulin G constitutes 75 % of serum immunoglobulins. Immunoglobulin G binds to viruses, bacteria, as well as fungi and facilitates their destruction or neutralization via agglutination (and thereby immobilizing them), activation of the compliment cascade, and opsinization for phagocytosis. IgG1 is the most abundant of the four IgG subclasses. This isotype control possesses lambda light chains.
Synonyms: Mouse immunoglobulin gamma lambda, Mouse IgG1 isotype control
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