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Rat IgG Isotype Control

IsoC, ELISA, WB IgG Native unconjugated Fc fragment
Catalog No. ABIN964381
  • Target See all IgG products
    IgG
    Antibody Type
    Native
    Fragment
    Fc fragment
    Host
    • 134
    • 128
    • 117
    • 86
    • 82
    • 56
    • 47
    • 46
    • 44
    • 43
    • 38
    • 37
    • 34
    • 33
    • 27
    • 21
    • 15
    • 15
    • 9
    • 9
    • 4
    • 2
    Rat
    Application
    Isotype Control (IsoC), ELISA, Western Blotting (WB)
    Characteristics
    Concentration Definition: by UV absorbance at 280 nm
    Isotype
    IgG
  • Application Notes
    Rat IgG F(c) Fragment can be utilized as a control or standard reagent in Western Blotting and ELISA experiments.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Preservative
    Sodium azide
    Precaution of Use
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    Storage
    4 °C
  • Target
    IgG
    Abstract
    IgG Products
    Target Type
    Antibody
    Background
    Secreted as part of the adaptive immune response by plasma B cells, immunoglobulin G constitutes 75 % of serum immunoglobulins. Immunoglobulin G binds to viruses, bacteria, as well as fungi and facilitates their destruction or neutralization via agglutination (and thereby immobilizing them), activation of the compliment cascade, and opsinization for phagocytosis. The F(c) fragment binds with very high affinity to the Fc receptor proteins on phagocytic leukocytes. When digested from the whole antibody molecule, the F(c) fragment no longer posses the epitope recognition site.

    Synonyms: Rat Immunoglobulin G F(c) fragment, IgG Fc
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