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ISL1 Products

(ISL LIM Homeobox 1 (ISL1))

Categories

This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq, Jul 2008].

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Featured ISL1 Categories

ISL1 Antibodies

High quality antibodies with extensive validation data.

ISL1 ELISA Kits

Reliable ELISA kits for a wide range of species.

ISL1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ISL1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, RNAi
Validations
  • (5)
Cat. No. ABIN561533
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (5)
  • (4)
Cat. No. ABIN561536
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, ICC
Validations
  • (1)
  • (3)
Cat. No. ABIN969219
Quantity 100 μL
Datasheet Datasheet

Recommended ISL1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957217
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4883461
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6385992
Quantity 96 tests
Datasheet Datasheet

Recommended ISL1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123637
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308138
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1780323
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our ISL1 products

Tian, Wang, Lu, Chen, Ma, Jia, Zhou: "Cross-talk of SFRP4, integrin α1β1, and Notch1 inhibits cardiac differentiation of P19CL6 cells." in: Cellular signalling, Vol. 28, Issue 11, pp. 1806-15, (2016) (PubMed).

Iglesias-Gato, Chuan, Jiang, Svensson, Bao, Paul, Egevad, Kessler, Wikström, Niu, Flores-Morales: "OTUB1 de-ubiquitinating enzyme promotes prostate cancer cell invasion in vitro and tumorigenesis in vivo." in: Molecular cancer, Vol. 14, pp. 8, (2015) (PubMed).

Zhang, Yang, Wang, Guo, Jia, Ma, Zhou: "A positive feedback regulation of ISL-1 in DLBCL but not in pancreatic ?-cells." in: Biochemical and biophysical research communications, Vol. 449, Issue 3, pp. 295-300, (2014) (PubMed).

Zhang, Yang, Jia, Liu, Guo, Lu, Chen, Ma, Wang, Zhou: "ISL-1 is overexpressed in non-Hodgkin lymphoma and promotes lymphoma cell proliferation by forming a p-STAT3/p-c-Jun/ISL-1 complex." in: Molecular cancer, Vol. 13, pp. 181, (2014) (PubMed).

Qu, Li, Louis, Li, Yang, Sun, Crandall, Tsang, Zhou, Cox, Cheng, Wang: "High-efficiency motor neuron differentiation from human pluripotent stem cells and the function of Islet-1." in: Nature communications, Vol. 5, pp. 3449, (2014) (PubMed).

Sizarov, Lamers, Mohun, Brown, Anderson, Moorman: "Three-dimensional and molecular analysis of the arterial pole of the developing human heart." in: Journal of anatomy, Vol. 220, Issue 4, pp. 336-49, (2012) (PubMed).

Li, Jia, Wang, Wang, Zhang, Chen, Ma, Zhou: "Interaction of Wnt/?-catenin and notch signaling in the early stage of cardiac differentiation of P19CL6 cells." in: Journal of cellular biochemistry, Vol. 113, Issue 2, pp. 629-39, (2012) (PubMed).

Guo, Wang, Zhang, Liu, Chen, Ma, Zhou: "ISL1 promotes pancreatic islet cell proliferation." in: PLoS ONE, Vol. 6, Issue 8, pp. e22387, (2011) (PubMed).

Emre, Vidal, Elia, OConnor, Paramban, Hefferan, Navarro, Goldberg, Varki, Marsala, Carson: "The ROCK inhibitor Y-27632 improves recovery of human embryonic stem cells after fluorescence-activated cell sorting with multiple cell surface markers." in: PLoS ONE, Vol. 5, Issue 8, pp. e12148, (2010) (PubMed).

Xu, Police, Hassanipour, Li, Chen, Priest, OSullivan, Laflamme, Zhu, Van Biber, Hegerova, Yang, Delavan-Boorsma, Davies, Lebkowski, Gold: "Efficient generation and cryopreservation of cardiomyocytes derived from human embryonic stem cells." in: Regenerative medicine, Vol. 6, Issue 1, pp. 53-66, (2010) (PubMed).

Synonyms and alternative names related to ISL1

ISL LIM homeobox 1 S homeolog (isl1.S), ISL LIM homeobox 1 (ISL1), ISL LIM homeobox 1 (Isl1), ISL1 transcription factor, LIM/homeodomain (Isl1), ISL LIM homeobox 1 (isl1), Isl-1, isl-1=homeobox, ISLET-1, islet-1, Islet-1, islet1, ISLET1, Xisl-1, Xislet-1

Protein level used designations for ISL1

  • islet-1
  • ISL1 transcription factor, LIM/homeodomain, (islet-1)
  • domesticus (clone 1.7 kB) islet-1
  • insulin gene enhancer protein ISL-1
  • ISL1 transcription factor, LIM/homeodomain
  • ISL1 transcription factor LIM/homeodomain (islet-1)
  • ISL1 transcription factor, LIM/homeodomain 1
  • isl-1 homeobox
  • Insulin gene enhancer protein ISL-1
  • Islet 1
  • Lim-homeodomain protein Islet1
  • insulin related protein
  • insulin gene enhancer protein isl-1
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