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ISG20 Products

(Interferon Stimulated Exonuclease Gene 20kDa (ISG20))

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Exonuclease with specificity for single-stranded RNA and, to a lesser extent for DNA. Degrades RNA at a rate that is approximately 35-fold higher than its rate for single-stranded DNA. May be involved in the antiviral function of IFN against RNA viruses (By similarity). Besides its function in antiviral defense, ISG20 may play additional roles in the maturation of snRNAs and rRNAs, and in ribosome biogenesis (By similarity).

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Featured ISG20 Categories

ISG20 Antibodies

High quality antibodies with extensive validation data.

ISG20 ELISA Kits

Reliable ELISA kits for a wide range of species.

ISG20 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ISG20 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (2)
  • (4)
Cat. No. ABIN561532
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IP
Validations
  • (4)
Cat. No. ABIN517239
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN517237
Quantity 100 μL
Datasheet Datasheet

Recommended ISG20 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN455506
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1138545
Quantity 96 tests
Datasheet Datasheet
Reactivity Pig
Analytical Method
Validations
Cat. No. ABIN1138546
Quantity 96 tests
Datasheet Datasheet

Recommended ISG20 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308135
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3082021
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3130277
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our ISG20 products

Zahoor, Xue, Sato, Murakami, Takeshima, Aida: "HIV-1 Vpr induces interferon-stimulated genes in human monocyte-derived macrophages." in: PLoS ONE, Vol. 9, Issue 8, pp. e106418, (2014) (PubMed).

Möller, Pion, Narayan, Ball: "Intracellular activation of interferon regulatory factor-1 by nanobodies to the multifunctional (Mf1) domain." in: The Journal of biological chemistry, Vol. 285, Issue 49, pp. 38348-61, (2010) (PubMed).

Zhou, Wang, Woodson, Dong, Wang, Liang, Rijnbrand, Wei, Nichols, Guo, Holbrook, Lemon, Li: "Antiviral activities of ISG20 in positive-strand RNA virus infections." in: Virology, Vol. 409, Issue 2, pp. 175-88, (2010) (PubMed).

Horio, Murai, Inoue, Hamasaki, Tanaka, Ohgi: "Crystal structure of human ISG20, an interferon-induced antiviral ribonuclease." in: FEBS letters, Vol. 577, Issue 1-2, pp. 111-6, (2004) (PubMed).

Synonyms and alternative names related to ISG20

interferon stimulated exonuclease gene 20 (ISG20), interferon stimulated exonuclease gene 20 (Isg20), interferon-stimulated protein (Isg20), 20kDa, 1600023I01Rik, 2010107M23Rik, CD25, DnaQL, HEM45, ISG20

Protein level used designations for ISG20

  • interferon stimulated exonuclease gene 20kDa
  • interferon stimulated exonuclease 20
  • interferon stimulated gene 20kDa
  • interferon-stimulated gene 20 kDa protein
  • interferon-stimulated protein
  • estrogen-regulated transcript 45 protein
  • promyelocytic leukemia nuclear body-associated protein ISG20
  • interferon stimulated exonuclease
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