IRS4 Products
(Insulin Receptor Substrate 4 (IRS4))
Categories
IRS4 encodes the insulin receptor substrate 4, a cytoplasmic protein that contains many potential tyrosine and serine/threonine phosphorylation sites. Tyrosine-phosphorylated IRS4 protein has been shown to associate with cytoplasmic signalling molecules that contain SH2 domains. The IRS4 protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation.. [provided by RefSeq, Jul 2008].
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Featured IRS4 Categories
IRS4 Antibodies
High quality antibodies with extensive validation data.
IRS4 ELISA Kits
Reliable ELISA kits for a wide range of species.
IRS4 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IRS4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN563643
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, ELISA, IF
Validations
- (1)
- (1)
Cat. No.
ABIN5539610
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
IF (cc), IF (p), ELISA, IHC (fro), IHC (p)
Validations
- (1)
Cat. No.
ABIN726020
Quantity
100 μL
Datasheet
Datasheet
Recommended IRS4 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5592818
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN454314
Quantity
96 tests
Datasheet
Datasheet
Recommended IRS4 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308110
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7419889
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7419892
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our IRS4 products
: "IRS4 induces mammary tumorigenesis and confers resistance to HER2-targeted therapy through constitutive PI3K/AKT-pathway hyperactivation." in: Nature communications, Vol. 7, pp. 13567, (2018) (PubMed).: "Oncogenic transformation by the signaling adaptor proteins insulin receptor substrate (IRS)-1 and IRS-2." in: Cell cycle (Georgetown, Tex.), Vol. 6, Issue 6, pp. 705-13, (2007) (PubMed).
: "IRS proteins and the common path to diabetes." in: American journal of physiology. Endocrinology and metabolism, Vol. 283, Issue 3, pp. E413-22, (2002) (PubMed).
: "IRS proteins and beta-cell function." in: Diabetes, Vol. 50 Suppl 1, pp. S140-5, (2001) (PubMed).
Synonyms and alternative names related to IRS4
insulin receptor substrate 4 (IRS4), insulin receptor substrate 4 (irs4), insulin receptor substrate 4 (Irs4), insulin receptor substrate 4 S homeolog (irs4.S), irs-4, IRS-4, irs2, irs2-a, IRS4, py160, PY160Protein level used designations for IRS4
- insulin receptor substrate 4
- 160 kDa phosphotyrosine protein
- phosphoprotein of 160 kDa
- pp160
- IRS-2-A
- insulin receptor substrate 2-A
- insulin receptor substrate protein
- insulin receptor substrate-undetermined designation
- insulin receptor substrate-unique
- xIRS-u
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