IRS2 Products
(Insulin Receptor Substrate 2 (IRS2))
Categories
This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. [provided by RefSeq, Jul 2008].
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Featured IRS2 Categories
IRS2 Antibodies
High quality antibodies with extensive validation data.
IRS2 ELISA Kits
Reliable ELISA kits for a wide range of species.
IRS2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IRS2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (p), IF
Validations
- (4)
Cat. No.
ABIN392217
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7443698
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7156336
Quantity
100 μg
Datasheet
Datasheet
Recommended IRS2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6956772
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967616
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956770
Quantity
96 tests
Datasheet
Datasheet
Recommended IRS2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123447
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308108
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7406728
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our IRS2 products
: "Regulation of insulin receptor phosphorylation in the brains of prenatally stressed rats: New insight into the benefits of antidepressant drug treatment." in: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, Vol. 27, Issue 2, pp. 120-131, (2017) (PubMed).: "Defective insulin signaling and the protective effects of dimethyldiguanide during follicular development in the ovaries of polycystic ovary syndrome." in: Molecular medicine reports, Vol. 16, Issue 6, pp. 8164-8170, (2017) (PubMed).
: "Donor Graft MicroRNAs: A Newly Identified Player in the Development of New-onset Diabetes After Liver Transplantation." in: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, Vol. 17, Issue 1, pp. 255-264, (2016) (PubMed).
: "Recurrent Amplification at 13q34 Targets at CUL4A, IRS2, and TFDP1 As an Independent Adverse Prognosticator in Intrahepatic Cholangiocarcinoma." in: PLoS ONE, Vol. 10, Issue 12, pp. e0145388, (2015) (PubMed).
: "Oncogenic transformation by the signaling adaptor proteins insulin receptor substrate (IRS)-1 and IRS-2." in: Cell cycle (Georgetown, Tex.), Vol. 6, Issue 6, pp. 705-13, (2007) (PubMed).
: "Protein kinase C Theta inhibits insulin signaling by phosphorylating IRS1 at Ser(1101)." in: The Journal of biological chemistry, Vol. 279, Issue 44, pp. 45304-7, (2004) (PubMed).
: "IRS proteins and the common path to diabetes." in: American journal of physiology. Endocrinology and metabolism, Vol. 283, Issue 3, pp. E413-22, (2002) (PubMed).
: "IRS proteins and beta-cell function." in: Diabetes, Vol. 50 Suppl 1, pp. S140-5, (2001) (PubMed).
Synonyms and alternative names related to IRS2
insulin receptor substrate 2 (IRS2), insulin receptor substrate 2a (irs2a), insulin receptor substrate 2b (irs2b), insulin receptor substrate 2 (Irs2), 4PS, IRS-2, Irs-2, IRS2, si:dkeyp-24d6.1Protein level used designations for IRS2
- insulin receptor substrate 2
- tyrosine kinase substrate
- 4PS
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