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IRF5 Products

(Interferon Regulatory Factor 5 (IRF5))

Categories

This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. [provided by RefSeq, Mar 2010].

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Featured IRF5 Categories

IRF5 Antibodies

High quality antibodies with extensive validation data.

IRF5 ELISA Kits

Reliable ELISA kits for a wide range of species.

IRF5 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IRF5 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IP, IF
Validations
  • (6)
Cat. No. ABIN561528
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (4)
Cat. No. ABIN184812
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (4)
Cat. No. ABIN517230
Quantity 50 μg
Datasheet Datasheet

Recommended IRF5 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6956913
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956914
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6951149
Quantity 96 tests
Datasheet Datasheet

Recommended IRF5 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123498
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123497
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308090
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our IRF5 products

Idborg, Zandian, Ossipova, Wigren, Preger, Mobarrez, Checa, Sohrabian, Pucholt, Sandling, Fernandes-Cerqueira, Rönnelid, Oke, Grosso, Kvarnström, Larsson, Wheelock, Syvänen, Rönnblom, Kultima et al.: "Circulating Levels of Interferon Regulatory Factor-5 Associates With Subgroups of Systemic Lupus Erythematosus Patients. ..." in: Frontiers in immunology, Vol. 10, pp. 1029, (2019) (PubMed).

Al Mamun, Chauhan, Yu, Xu, Sharmeen, Liu: "Interferon regulatory factor 4/5 signaling impacts on microglial activation after ischemic stroke in mice." in: The European journal of neuroscience, Vol. 47, Issue 2, pp. 140-149, (2018) (PubMed).

Yamaguchi, Yamamoto, Sakamoto, Ishimaru, Narahara, Sugiuchi, Yamaguchi: "A protease-activated receptor 2 agonist (AC-264613) suppresses interferon regulatory factor 5 and decreases interleukin-12p40 production by lipopolysaccharide-stimulated macrophages: Role of p53." in: Cell biology international, Vol. 40, Issue 6, pp. 629-41, (2016) (PubMed).

Li, De, Li, Song, Matta, Barnes: "Specific detection of interferon regulatory factor 5 (IRF5): A case of antibody inequality." in: Scientific reports, Vol. 6, pp. 31002, (2016) (PubMed).

Griesbeck, Ziegler, Laffont, Smith, Chauveau, Tomezsko, Sharei, Kourjian, Porichis, Hart, Palmer, Sirignano, Beisel, Hildebrandt, Cénac, Villani, Diefenbach, Le Gall, Schwartz, Herbeuval, Autran et al.: "Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-α Production in Women. ..." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 11, pp. 5327-36, (2015) (PubMed).

Hanke, Angle, Kielian: "MyD88-dependent signaling influences fibrosis and alternative macrophage activation during Staphylococcus aureus biofilm infection." in: PLoS ONE, Vol. 7, Issue 8, pp. e42476, (2012) (PubMed).

Bi, Hameed, Mirani, Pimenta, Anari, Barnes: "Loss of interferon regulatory factor 5 (IRF5) expression in human ductal carcinoma correlates with disease stage and contributes to metastasis." in: Breast cancer research : BCR, Vol. 13, Issue 6, pp. R111, (2012) (PubMed).

Krausgruber, Saliba, Ryzhakov, Lanfrancotti, Blazek, Udalova: "IRF5 is required for late-phase TNF secretion by human dendritic cells." in: Blood, Vol. 115, Issue 22, pp. 4421-30, (2010) (PubMed).

Hu, Barnes: "IRF-5 is a mediator of the death receptor-induced apoptotic signaling pathway." in: The Journal of biological chemistry, Vol. 284, Issue 5, pp. 2767-77, (2009) (PubMed).

Coletta, Cullington, Clark, Cleland: "Clinical trials update from European Society of Cardiology meeting 2008: TIME-CHF, BACH, BEAUTIFUL, GISSI-HF, and HOME-HF." in: European journal of heart failure, Vol. 10, Issue 12, pp. 1264-7, (2008) (PubMed).

Synonyms and alternative names related to IRF5

interferon regulatory factor 5 (IRF5), interferon regulatory factor 5 (irf5), interferon regulatory factor 5 (Irf5), interferon regulatory factor 5 L homeolog (irf5.L), AW491843, im:7155364, IRF5, irf5, mirf5, SLEB10, zgc:76986

Protein level used designations for IRF5

  • interferon regulatory factor 5
  • Interferon regulatory factor 5
  • interferon regulatory factor 5-like
  • IRF-5
  • interferon regulatory factor 5 bone marrow
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