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Zebularine

Inh 3690-10-6 1H-β-D-ribofuranosyl-2-pyrimidinone
Catalog No. ABIN7233307
  • Application
    Inhibition (Inh)
    Purpose
    DNA methylation inhibitor
    Characteristics
    Orally active DNA methyltransferase inhibitor. Inhibits tumor cell proliferation (IC50 = 120 μM) and re-activates silenced genes in T24 bladder carcinoma cells. Inhibits cytidine deaminase (Ki ~ 2 μM), induces differentiation of mesenchymal stem cells into cardiomyocytes.
    Purity
    >98 %
    Chemical Name
    1H-β-D-ribofuranosyl-2-pyrimidinone
    Formula
    C9H12N2O5
    Solubility
    Soluble in DMSO (up to 20 mg/ml) or in Water (up to 20 mg/ml).
  • Restrictions
    For Research Use only
  • Format
    Powder
    Storage
    -20 °C
  • Background
    NSC 309132,Epigenetics,DNA damage,DNA methyltransferase,Stem cells,Infectious disease,Cancer,Chromatin,Proliferation
    Molecular Weight
    228.21
    CAS-No
    3690-10-6
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