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SGC-707

Inh Cell-permeable 1687736-54-4 1-Isoquinolin-6-yl-3-(2-oxo-2-pyrrolidin-1-yl-ethyl)-urea
Catalog No. ABIN7233288
  • Application
    Inhibition (Inh)
    Purpose
    PRMT3 inhibitor
    Characteristics
    Potent and selective allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3).1 IC50 = 31 nM and selective against 31 other methyltransferases. An extremely useful probe for investigating the role of PRMT3 in normal and pathophysiology. Cell permeable and active in vivo.
    Purity
    >98 %
    Chemical Name
    1-Isoquinolin-6-yl-3-(2-oxo-2-pyrrolidin-1-yl-ethyl)-urea
    Formula
    C16H18N4O2
    Permeability
    Cell-permeable
    Solubility
    Soluble in DMSO (up to 35 mg/ml)
  • Restrictions
    For Research Use only
  • Format
    Powder
    Storage
    -20 °C
  • Background
    Epigenetics,Protein methyltransferase,Posttranslational modification,Chromatin
    Molecular Weight
    298.34
    CAS-No
    1687736-54-4
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