BAY 11-7082
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- Application
- Inhibition Assay (InhA), Functional Studies (Func)
- Purpose
- BAY 11-7082 is a NF-κB inhibitor, inhibits TNFα-induced IκBα phosphorylation with IC50 of 10 μM in tumor cells. Also inhibiting components of the ubiquitin system.
- Characteristics
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Tradename: (E)-3-Tosylacrylonitrile
Target: IκB/IKK inhibitor
Receptor: IκBα phosphorylation - Purification
- All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
- Purity
- 98 %
- Formula
- C10H9NO2S
- Solubility
- Soluble in DMSO, water, ethanol
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Solid
- Storage
- -20 °C
- Storage Comment
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For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours. - Expiry Date
- 24 months
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- Background
- Immunology/Inflammation
- Molecular Weight
- 207.25 g/mol
- CAS-No
- 19542-67-7
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