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Suramin Sodium Salt

InhA, Func 129-46-4
Catalog No. ABIN4876545
  • Application
    Inhibition Assay (InhA), Functional Studies (Func)
    Purpose
    Suramin sodium salt is a polysulfonated naphthylurea that inhibits the binding of calmodulin to recognition sites on the ryanodine receptor-1 (IC50 = 4.9 μM), blocks G protein coupling to GPCRs, and non-selectively antagonizes P2 purinergic receptors (10-100 μM).
    Characteristics
    Target: P2 Receptor inhibitor
    Receptor: P2Y Receptor
    Purification
    All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
    Purity
    99.60 %
    Formula
    C51H34N6O23S6
    Solubility
    10 mM in DMSO
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Solid
    Storage
    -20 °C
    Storage Comment
    For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
    Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
    Several freeze/thaw cycles should not damage the activity of our small molecule products.
    However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
    Expiry Date
    24 months
  • Background
    Neuroscience
    Molecular Weight
    1291.34 g/mol
    CAS-No
    129-46-4
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