Integrin beta 2 Products
(Integrin beta 2 (ITGB2))
Categories
The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008].
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Featured Integrin beta 2 Categories
Integrin beta 2 Antibodies
High quality antibodies with extensive validation data.
Integrin beta 2 ELISA Kits
Reliable ELISA kits for a wide range of species.
Integrin beta 2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Integrin beta 2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
FACS, WB, IP, IHC (fro), IHC (p)
Validations
- (5)
- (6)
Cat. No.
ABIN94005
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
FACS, WB, IP, Func, IHC (fro), IHC (p)
Validations
- (5)
- (6)
Cat. No.
ABIN2749019
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
FACS, WB, IP, IHC (fro), IHC (p)
Validations
- (5)
- (5)
Cat. No.
ABIN94007
Quantity
0.1 mg
Datasheet
Datasheet
Recommended Integrin beta 2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (5)
Cat. No.
ABIN6574283
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967700
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967699
Quantity
96 tests
Datasheet
Datasheet
Recommended Integrin beta 2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308201
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308205
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Baculovirus infected Insect Cells
Validations
- (1)
Cat. No.
ABIN5854581
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our Integrin beta 2 products
: "Hypoxia and matrix viscoelasticity sequentially regulate endothelial progenitor cluster-based vasculogenesis." in: Science advances, Vol. 5, Issue 3, pp. eaau7518, (2019) (PubMed).: "The Extracellular Domain of the β2 Integrin β Subunit (CD18) Is Sufficient for Escherichia coli Hemolysin and Aggregatibacter actinomycetemcomitans Leukotoxin Cytotoxic Activity." in: mBio, Vol. 10, Issue 4, (2019) (PubMed).
: "Protective effects of sinomenine against LPS-induced inflammation in piglets." in: Microbial pathogenesis, Vol. 110, pp. 573-577, (2018) (PubMed).
: "Synthesis of Human Neutrophil Extracellular Traps Contributes to Angiopoietin-Mediated In Vitro Proinflammatory and Proangiogenic Activities." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 11, pp. 3801-3813, (2018) (PubMed).
: "Biomimetic post-capillary venule expansions for leukocyte adhesion studies." in: Scientific reports, Vol. 8, Issue 1, pp. 9328, (2018) (PubMed).
: "Origin-Specific Adhesive Interactions of Mesenchymal Stem Cells with Platelets Influence Their Behavior After Infusion." in: Stem cells (Dayton, Ohio), Vol. 36, Issue 7, pp. 1062-1074, (2018) (PubMed).
: "Bystander cells enhance NK cytotoxic efficiency by reducing search time." in: Scientific reports, Vol. 7, pp. 44357, (2017) (PubMed).
: "Dynamin2 controls Rap1 activation and integrin clustering in human T lymphocyte adhesion." in: PLoS ONE, Vol. 12, Issue 3, pp. e0172443, (2017) (PubMed).
: "P-selectin-mediated platelet adhesion promotes tumor growth." in: Oncotarget, Vol. 6, Issue 9, pp. 6584-96, (2015) (PubMed).
: "Local but Not Systemic Administration of Uridine Prevents Development of Antigen-Induced Arthritis." in: PLoS ONE, Vol. 10, Issue 10, pp. e0141863, (2015) (PubMed).
Synonyms and alternative names related to Integrin beta 2
integrin subunit beta 2 (ITGB2), integrin beta 2 (Itgb2), integrin subunit beta 2 (Itgb2), integrin subunit beta 2 S homeolog (itgb2.S), 2E6, AI528527, CD18, Cd18, ITGB2, itgb2, itgb2-a, itgb2-b, LAD, LCAMB, LFA-1, Lfa1, MAC-1, MF17, MFI7Protein level used designations for Integrin beta 2
- cell surface adhesion glycoprotein LFA-1/CR3/P150,959 beta subunit precursor)
- cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta
- complement receptor C3 beta-subunit
- complement receptor C3 subunit beta
- integrin beta chain, beta 2
- integrin beta-2
- leukocyte cell adhesion molecule CD18
- leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C
- Mac-1 beta
- lymphocyte function associated antigen 1
- macrophage antigen-1 beta
- CD18 subunit
- Leu-CAM receptor
- integrin, beta 2 (antigen CD18 subunit (p95), lymphocyte function-associated antigen 1, integrin B2)
- integrin beta 2 subunit
- CD18 leukocyte adhesion molecule
- antigen CD18
- integrin beta-2 chain
- integrin beta 2
- integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1
- integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
- macrophage antigen 1 (mac-1) beta subunit)
- Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta
- Complement receptor C3 subunit beta
- Integrin beta-2
- integrin beta-2 subunit
- integrin subunit beta 2 S homeolog
- integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
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