Integrin Alpha2b Products
(Integrin Alpha2b (CD41))
Categories
ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq, Jul 2008].
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Featured Integrin Alpha2b Categories
Integrin Alpha2b Antibodies
High quality antibodies with extensive validation data.
Integrin Alpha2b ELISA Kits
Reliable ELISA kits for a wide range of species.
Integrin Alpha2b Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Integrin Alpha2b Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
FACS, WB, ELISA, IHC
Validations
- (2)
- (6)
Cat. No.
ABIN1724822
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
FACS, WB, ELISA, IHC (fro), IHC (p), IF (p), IF (cc)
Validations
- (4)
- (3)
Cat. No.
ABIN748358
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
FACS, ELISA, IHC (fro), IP, IHC (p), Func
Validations
- (4)
- (2)
Cat. No.
ABIN2749191
Quantity
0.1 mg
Datasheet
Datasheet
Recommended Integrin Alpha2b ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6956844
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967696
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967695
Quantity
96 tests
Datasheet
Datasheet
Recommended Integrin Alpha2b Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN2565087
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7411633
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN5709771
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Integrin Alpha2b products
: "Tetraspanins distinguish separate extracellular vesicle subpopulations in human serum and plasma - Contributions of platelet extracellular vesicles in plasma samples." in: Journal of extracellular vesicles, Vol. 11, Issue 5, pp. e12213, (2022) (PubMed).: "Platelet activation in experimental murine neonatal pulmonary hypertension." in: Physiological reports, Vol. 8, Issue 5, pp. e14386, (2020) (PubMed).
: "Cysteinyl leukotriene receptor 2 drives lung immunopathology through a platelet and high mobility box 1-dependent mechanism." in: Mucosal immunology, Vol. 12, Issue 3, pp. 679-690, (2019) (PubMed).
: "Drug-induced activation of integrin alpha IIb beta 3 leads to minor localized structural changes." in: PLoS ONE, Vol. 14, Issue 4, pp. e0214969, (2019) (PubMed).
: "iTRAQ-Based Proteomic Analysis Reveals Protein Profile in Plasma from Children with Autism." in: Proteomics. Clinical applications, Vol. 12, Issue 3, pp. e1700085, (2019) (PubMed).
: "IQCA-TAVV: To explore the effect of P-selectin, GPIIb/IIIa, IL-2, IL-6 and IL-8 on deep venous thrombosis." in: Oncotarget, Vol. 8, Issue 53, pp. 91391-91401, (2017) (PubMed).
: "Aerobic exercise in humans mobilizes HSCs in an intensity-dependent manner." in: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 122, Issue 1, pp. 182-190, (2017) (PubMed).
: "New evidence that a large proportion of human blood plasma cell-free DNA is localized in exosomes." in: PLoS ONE, Vol. 12, Issue 8, pp. e0183915, (2017) (PubMed).
: "Biodistribution Analysis of Oncolytic Adenoviruses in Patient Autopsy Samples Reveals Vascular Transduction of Noninjected Tumors and Tissues." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 23, Issue 10, pp. 1641-52, (2016) (PubMed).
: "Influenza Virus Infection Induces Platelet-Endothelial Adhesion Which Contributes to Lung Injury." in: Journal of virology, Vol. 90, Issue 4, pp. 1812-23, (2016) (PubMed).
Synonyms and alternative names related to Integrin Alpha2b
integrin alpha 2b (Itga2b), integrin subunit alpha 2b (ITGA2B), AI172977, alphaIIb, BDPLT2, BDPLT16, CD41, CD41B, GP2B, GpIIb, GPIIb, GT, GTA, HPA3Protein level used designations for Integrin Alpha2b
- GP IIb
- GPalpha IIb
- alpha IIb
- integrin alpha-IIb
- platelet glycoprotein IIb of IIb/II Ia complex
- platelet membrane glycoprotein IIb
- platelet fibrinogen receptor, alpha subunit
- platelet-specific antigen BAK
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