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INPP5E Products

(Inositol Polyphosphate-5-Phosphatase, 72 KDa (INPP5E))

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The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. Studies of the mouse counterpart suggest that this protein may hydrolyze phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,5-bisphosphate on the cytoplasmic Golgi membrane and thereby regulate Golgi-vesicular trafficking. Mutations in this gene cause Joubert syndrome\; a clinically and genetically heterogenous group of disorders characterized by midbrain-hindbrain malformation and various associated ciliopathies that include retinal dystrophy, nephronophthisis, liver fibrosis and polydactyly.[provided by RefSeq, Feb 2011].

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Featured INPP5E Categories

INPP5E Antibodies

High quality antibodies with extensive validation data.

INPP5E Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended INPP5E Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB
Validations
  • (1)
  • (1)
Cat. No. ABIN7298962
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7142862
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN7267883
Quantity 100 μL
Datasheet Datasheet

Recommended INPP5E ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6230291
Quantity 96 tests
Datasheet Datasheet

Recommended INPP5E Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307957
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2723486
Quantity 20 μg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1659061
Quantity 1 mg
Datasheet Datasheet

Synonyms and alternative names related to INPP5E

inositol polyphosphate-5-phosphatase E (Inpp5e), inositol polyphosphate-5-phosphatase E (INPP5E), 72kDa, 1200002L24Rik, CORS1, CPD4, JBTS1, mKIAA0123, MORMS, PMPCA, PPI5PIV

Protein level used designations for INPP5E

  • 72 kDa inositol polyphosphate 5-phosphatase
  • inositol polyphosphate-5-phosphatase, 72 kDa
  • phosphatidylinositol 4,5-bisphosphate 5-phosphatase
  • phosphatidylinositol polyphosphate 5-phosphatase type IV
  • phosphatidylinositol-4,5-bisphosphate 5-phosphatase
  • 5-phosphatase that induces arborization
  • inositol polyphosphate 5-phosphatase
  • pharbin
  • phosphatidylinositol (4,5) bisphosphate 5-phosphatase
  • inositol polyphosphate-5-phosphatase E
  • peptidase (mitochondrial processing) alpha
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