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INPP5D Proteins

(Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))
This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall, the protein functions as a negative regulator of myeliod cell proliferation and survival. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
INPP5D Protein (AA 1-1189) (Strep Tag) (ABIN3095410)

INPP5D Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant > 80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, SDS, WB

INPP5D Protein (AA 1-1191) (Strep Tag) (ABIN3137223)

INPP5D Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant > 80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, SDS, WB

INPP5D Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) INPP5D Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) INPP5D Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2723485)

INPP5D Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

INPP5D Proteins by Origin

Find INPP5D Proteins for a variety of species such as anti-Human INPP5D, anti-Mouse INPP5D. The species listed below are among those available. Click on a link to go to the corresponding products.

INPP5D Proteins by Source

Here you will find INPP5D Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

INPP5D Proteins by Protein Type

Here you can find INPP5D Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

INPP5D Proteins by Application

Find INPP5D Proteins validated for a specific application such as ELISA, SDS, WB, AbP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular INPP5D Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3095410
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3137223
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2723485
Quantity 20 μg
Datasheet Datasheet

Aliases for INPP5D Proteins

inositol polyphosphate-5-phosphatase D (INPP5D) Proteins
phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (LOC100446045) Proteins
inositol polyphosphate-5-phosphatase D (inpp5d) Proteins
inositol polyphosphate 5-phosphatase (EHI_159880) Proteins
inositol polyphosphate 5-phosphatase (EHI_153490) Proteins
inositol polyphosphate-5-phosphatase D L homeolog (inpp5d.L) Proteins
phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (LOC100380693) Proteins
inositol polyphosphate-5-phosphatase D (Inpp5d) Proteins
13.t00027 Proteins
256.t00004 Proteins
AI323613 Proteins
hp51CN Proteins
INPP5D Proteins
s-SHIP Proteins
ship Proteins
SHIP Proteins
SHIP-1 Proteins
ship1 Proteins
SHIP1 Proteins
SIP-145 Proteins
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