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Importin 8 Products

(Importin 8 (IPO8))

Categories

The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010].

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Featured Importin 8 Categories

Importin 8 Antibodies

High quality antibodies with extensive validation data.

Importin 8 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Importin 8 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN7267859
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application IHC, WB, IP, ICC
Validations
  • (3)
Cat. No. ABIN7442759
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IF
Validations
  • (3)
Cat. No. ABIN7258042
Quantity 200 μL
Datasheet Datasheet

Recommended Importin 8 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308019
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7415416
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3093230
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Importin 8 products

Li, Song, Quach, Guo, Jang, Maazi, Zhao, Sands, Liu, In, Peng, Yuan, Machida, Yu, Akbari, Hagiya, Yang, Punj, Tang, Liang: "Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance." in: Nature communications, Vol. 10, Issue 1, pp. 1693, (2019) (PubMed).

Perera, Stoykova, Nicolay, Ross, Fitamant, Boukhali, Lengrand, Deshpande, Selig, Ferrone, Settleman, Stephanopoulos, Dyson, Zoncu, Ramaswamy, Haas, Bardeesy: "Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism." in: Nature, Vol. 524, Issue 7565, pp. 361-5, (2015) (PubMed).

Wu, Wang, Young, Lai, Li: "Proteome-wide identification of novel binding partners to the oncogenic fusion gene protein, NPM-ALK, using tandem affinity purification and mass spectrometry." in: The American journal of pathology, Vol. 174, Issue 2, pp. 361-70, (2009) (PubMed).

Görlich, Dabrowski, Bischoff, Kutay, Bork, Hartmann, Prehn, Izaurralde: "A novel class of RanGTP binding proteins." in: The Journal of cell biology, Vol. 138, Issue 1, pp. 65-80, (1997) (PubMed).

Synonyms and alternative names related to Importin 8

importin 8 (IPO8), importin 8 (ipo8), importin 8 (Ipo8), 6230418K12Rik, Abcc10, C130009K11Rik, IPO8, MRP7, OM-1, Om1, RANBP8, Ranbp8, si:ch211-116i17.1

Protein level used designations for Importin 8

  • importin 8
  • importin-8
  • RAN binding protein 8
  • imp8
  • ran-binding protein 8
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 10
  • oocyte maturation 1
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