IMPDH2 Products
(IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))
Categories
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008].
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Featured IMPDH2 Categories
IMPDH2 Antibodies
High quality antibodies with extensive validation data.
IMPDH2 ELISA Kits
Reliable ELISA kits for a wide range of species.
IMPDH2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IMPDH2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IP, RNAi
Validations
- (1)
- (4)
Cat. No.
ABIN561488
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
Cat. No.
ABIN7156292
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (4)
Cat. No.
ABIN2855167
Quantity
100 μL
Datasheet
Datasheet
Recommended IMPDH2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967575
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967574
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956714
Quantity
96 tests
Datasheet
Datasheet
Recommended IMPDH2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1307895
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123412
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7408207
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our IMPDH2 products
: "Myc-dependent purine biosynthesis affects nucleolar stress and therapy response in prostate cancer." in: Oncotarget, Vol. 6, Issue 14, pp. 12587-602, (2015) (PubMed).: "IMPDH2 mediate radioresistance and chemoresistance in osteosarcoma cells." in: European review for medical and pharmacological sciences, Vol. 18, Issue 20, pp. 3038-44, (2014) (PubMed).
: "A purine nucleotide biosynthesis enzyme guanosine monophosphate reductase is a suppressor of melanoma invasion." in: Cell reports, Vol. 5, Issue 2, pp. 493-507, (2013) (PubMed).
: "Proteomic analysis of the effects of the immunomodulatory mycotoxin deoxynivalenol." in: Proteomics, Vol. 11, Issue 10, pp. 1903-14, (2011) (PubMed).
: "Antiproliferative effects of AVN944, a novel inosine 5-monophosphate dehydrogenase inhibitor, in prostate cancer cells." in: International journal of cancer, Vol. 123, Issue 10, pp. 2294-302, (2008) (PubMed).
: "Direct role of nucleotide metabolism in C-MYC-dependent proliferation of melanoma cells." in: Cell cycle (Georgetown, Tex.), Vol. 7, Issue 15, pp. 2392-400, (2008) (PubMed).
: "Prognostic significance of drug-regulated genes in high-grade osteosarcoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 20, Issue 10, pp. 1085-94, (2007) (PubMed).
Synonyms and alternative names related to IMPDH2
inosine monophosphate dehydrogenase 2 (IMPDH2), IMP (inosine 5'-monophosphate) dehydrogenase 2 (impdh2.S), IMP (inosine 5'-monophosphate) dehydrogenase 2 (impdh2), inosine monophosphate dehydrogenase 2 (impdh2), inosine monophosphate dehydrogenase 2 (Impdh2), inosine 5'-phosphate dehydrogenase 2 (impdh2), cb635, imp2, IMPD, impd2, IMPD2, IMPD 2, impdh-ii, IMPDH-II, impdh2, IMPDH 2, wu:fb64g02, wu:fc43f09Protein level used designations for IMPDH2
- IMP (inosine monophosphate) dehydrogenase 2
- inosine monophosphate dehydrogenase 2
- IMP (inosine 5'-monophosphate) dehydrogenase 2
- hCG2002013-like
- inosine-5'-monophosphate dehydrogenase 2-like
- IMP oxireductase 2
- IMPD 2
- IMPDH 2
- inosine 5' phosphate dehydrogenase 2
- inosine monophosphate dehydrogenase type II
- inosine-5'-monophosphate dehydrogenase 2
- IMP dehydrogenase 2
- IMPDH-II
- inosine 5'-phosphate dehydrogenase 2
- inosine 5-monophosphate dehydrogenase 2
- IMP dehydrogenase type II
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